Rabeprazole is a medicine used to reduce stomach acid and treat conditions like acid reflux, heartburn, and ulcers. It belongs to a group called proton pump inhibitors. Doctors often prescribe it for GERD (gastroesophageal reflux disease) and other acid-related stomach problems.

Rabeprazole helps relieve symptoms such as indigestion and prevents damage to the oesophagus caused by acid. It is also available in combination with domperidone to improve digestion. Always follow the doctor's advice for dosage and duration of use.

What Is Rabeprazole?

Rabeprazole, sold under the brand name Aciphex, is a drug that reduces stomach acid. It is used to treat peptic ulcer disease, gastroesophageal reflux disease, and excess stomach acid production, such as Zollinger-Ellison syndrome.You can consult experiencedgastroenterologists for accurate diagnosis and personalized treatment of acid-related disorders

Rabeprazole Tablet Uses

  • Rabeprazole is used to treat stomach and oesophagus problems like acid reflux and ulcers.
  • It reduces the production of stomach acid to alleviate symptoms such as difficulty swallowing, heartburn, and persistent coughing.
  • This medication helps rabeprazole gastro resistant tablet uses heal acid-related damage to the stomach and oesophagus, prevents ulcers, and can reduce the risk of oesophageal cancer.
  • Rabeprazole belongs to a class of drugs called proton pump inhibitors (PPIs), which are effective in managing acid-related disorders.

For comprehensive evaluation and endoscopic treatments, consult themedical gastroenterology department.

Conditions Rabeprazole Treats

  • Gastroesophageal Reflux Disease (GERD)
  • Peptic ulcers
  • Zollinger-Ellison syndrome
  • Erosive esophagitis
  • Helicobacter pylori infection (with antibiotics)

Secondary Uses of Rabeprazole

  • Relief from frequent heartburn
  • Supportive therapy in digestive disorders
  • Prevention of ulcer recurrence in long-term NSAID users

How Does Rabeprazole Work?

Rabeprazole works by reducing the amount of acid produced in the stomach. It blocks the proton pumps in stomach lining cells, which are responsible for acid secretion. This helps relieve symptoms like heartburn and allows ulcers and inflammation to heal. It does not directly affect hormones or the nervous system.

Rabeprazole Dosage

  • Take the medicine exactly as prescribed by your doctor.
  • The typical dose is 20 mg once daily before a meal.

What Should I Do If I Miss a Dose?

  • Take the missed Rabeprazole dose as soon as you remember.
  • If it is almost time for the next dose, skip the missed dose.
  • Do not take a double dose to make up for a missed one.

What Happens If an Overdose?

  • Overdose symptoms may include severe stomach pain, vomiting, or dizziness.
  • Seek immediate medical attention if overdose is suspected.

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Side Effects of Rabeprazole

Rabeprazole reduces stomach acid, which may lead to side effects such as headache, diarrhea, or nausea. Long-term use can affect mineral absorption (e.g., magnesium, calcium), increasing the risk of bone fractures or vitamin B12 deficiency.

Some of the common side effects of Rabeprazole are:

Precautions and Warnings

  • Pregnant or breastfeeding women should avoid using this medicine unless advised by a doctor.
  • Use caution in patients with liver problems or known allergies to rabeprazole or similar drugs.
  • Not recommended for children under 12 years without medical supervision.
  • Avoid alcohol while taking this medicine, as it may increase stomach irritation.

Possible Interactions with Other Medications (Drug Interactions)

  • Rabeprazole may interact with drugs like ketoconazole, warfarin, and atazanavir, altering their effects.
  • Combining with herbal supplements like St. John's Wort can reduce rabeprazoles effectiveness.

How Should Rabeprazole Be Stored?

  • Store at room temperature, between 20°C to 25°C (68°F to 77°F).
  • Keep away from moisture, heat, and direct sunlight.
  • Do not use if the medicine has expired or appears damaged.

What Happens If Rabeprazole Is Not Stored Properly?

  • Improper storage can reduce the medicines effectiveness.
  • It may also lead to contamination or spoilage, making it unsafe to use.

Rabeprazole vs Pantoprazole

Rabeprazole Pantoprazole
  • Formula: C18H21N3O3S
  • Brand name: Aciphex
  • Used to decrease stomach acid
  • Elimination half-life: 1 hour
  • Formula: C16H15F2N3O4S
  • Brand name: Protonix
  • Treats stomach and esophagus problems (e.g., acid reflux)
  • Elimination half-life: 1 to 2 hours

Reference:

Rabeprazole
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Frequently Asked Questions

It is used for acid reflux, heartburn, and gastro-oesophageal reflux disease (GORD). GORD is when you keep getting acid reflux. Rabeprazole is also used to prevent and treat stomach ulcers. Rabeprazole is sometimes used for a rare disease caused by a tumor in the pancreas or intestine called Zollinger-Ellison syndrome.

Rabeprazole side effects are:Headache,Pain in the abdomen (stomach area),Sore throat,Gas,Infection,Constipation,Diarrhea

Rabeprazole is for short-term use only, usually for 4 to 8 weeks. If you need extra time for healing, your doctor may recommend a second course of treatment.

Long-term use of rabeprazole may cause you to develop stomach growths called fundic gland polyps. Talk to your doctor about this risk. If you have been using rabeprazole for more than 3 years, you may develop vitamin B-12 deficiency. Talk to your doctor about how you can manage this condition if you develop it.

Check with your doctor right away if you have a change in the frequency of urine or urine, blood in your urine, fever, joint pain, loss of appetite, skin rash, swelling.

Rabeprazole tablets are specially coated so you should swallow them whole. Rabeprazole may be taken either before or after a meal, although it is preferable to take it before a meal. If you forget to take a dose at your usual time, you can usually take it when you remember.

In the present study, a meta-analysis revealed that rabeprazole 20 mg was more effective than omeprazole 20 mg in studies of up to 8 weeks of treatment to relieve the GERD symptom of heartburn. The results of this study favor rabeprazole 20 mg over omeprazole 20 mg in the relief of GERD-related heartburn.

The drug is effective in the treatment of gastroesophageal reflux disease (GERD) and other acid-related diseases. Long-term use of rabeprazole has been confirmed to be safe in studies of two to five-year maintenance therapy for GERD.

A low rate of transient and asymptomatic serum aminotransferase elevations is associated with rabeprazole therapy and is an uncommon source of clinically evident liver damage.

Allergic reactions – signs may include: sudden swelling of the face, difficulty breathing, or low blood pressure, which may cause fainting or collapse.


Disclaimer: The information provided is accurate and up-to-date to the best of our knowledge. However, it should not be considered a substitute for medical advice or consultation. We do not guarantee its completeness or accuracy. The absence of specific warnings does not mean a medicine is safe for all users. We are not responsible for any outcomes based on this information and strongly recommend consulting a doctor for any medical concerns or questions.

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