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By Medicover Hospitals / 11 Mar 2021
Home | Medicine | Lidocaine

What is Lidocaine?

  • Lidocaine, also known as lignocaine, is an amino amide-type local anesthetic. It is also employed in the treatment of ventricular tachycardia. When used for local anesthesia or nerve blocks, lidocaine usually starts working within few minutes and lasts between 30 minutes and three hours. Lidocaine is available in gels, creams, liquids, sprays, eye drops, and patches as a topical anaesthetic.
    1. Lidocaine
    2. Lidocaine Side effects
    3. Precautions
    4. Overdose
    5. Warnings
    6. Storage
    7. Lidocaine vs Bupivacaine
    8. Frequently Asked Questions
    9. Citations

    Lidocaine Uses:

  • This medication is used for applying on the skin to relieve itching and pain caused by certain skin conditions (such as scrapes, minor burns, eczema, insect bites), as well as to treat minor discomfort and itching caused by hemorrhoids and other genital/anal problems (e.g., anal fissures, itching around the vagina/rectum). Some forms of this medication are also used to alleviate discomfort or pain associated with certain medical procedures/exams (e.g., sigmoidoscopy, cystoscopy). Lidocaine is a local anaesthetic that works by temporarily numbing/deafening the skin and mucous membranes.
  • How to use:

    • Before using this medication, read and follow all directions on the product package if you are self-treating with an over-the-counter product. If your doctor has prescribed this medication, take it exactly prescribed.
    • Clean and dry the affected area as directed before applying it to the skin. Apply a thin layer of medication to the affected area of the skin two to three times per day, or as directed.
    • Before using the spray, give the canister a good shake. Spray until wet while holding the canister 3-5 inches (8-13 centimeters) away from the affected area. If the affected area is on your face, spray the medication on your hand and apply it to the affected area. Do not spray in your eyes, nose, and mouth.
    • If you're using foam, shake the canister thoroughly before using it. Apply the foam to the affected area with your hand.
    • Unless otherwise directed by your doctor, do not use on large areas of the body, cover the area with waterproof bandages or plastic, or apply heat. These may increase the likelihood of severe side effects.
    • Unless you are treating an area on your hands, wash your hands immediately after use. Try not to get the product in your eyes, nose, or ears. If the medication gets into these areas, immediately rinse them with clean water.
    • Do not use this medication if there is an infection or sore in the area to be treated without first consulting your doctor.

    Lidocaine Side Effects:

  • Some of the common side effects are:
    • Diarrhea
    • Stomach pain
    • Discomfort
    • Swelling
    • Nausea
    • Irritation
    • Vomiting
    • Loss of appetite
    • Itching
  • Some of the serious side effects are:
    • Seizures
    • Rash
    • Hives
    • Shortness of breath
    • Difficulty while breathing
    • Swallowing
    • Fever
    • Chills
  • Inform your doctor if you are having any serious health problems
  • Precautions:

    • Before taking this medicine talk with your doctor if you are allergic to it or any other medications related to it. The medication might contain some inactive ingredients which can cause some serious allergic reactions or some other serious health problems. Before taking the medications consult with your doctor if you are having any medical history such as Low blood count, Liver disease, intestinal problems, and kidney disease.
    • If you are scheduled for an MRI, notify the testing personnel that you are using this product. Some brands of this medication may contain metals that can cause serious burns during an MRI and should not be taken prior to the procedure. Inquire with your doctor or pharmacist if you have any questions about your specific brand
    • When using this drug in children, use caution because they may be more sensitive to the drug's side effects.
    • This medication should not be used during pregnancy. Consult your doctor about the risk factors and outcomes
    • This medication passes through breast milk, but it is unlikely to harm a nursing infant. Before breastfeeding, talk to your doctor.


  • Drug interactions can change the way your medicines work or put you at risk for adverse side effects. Maintain a list of all the products you use (including prescription and nonprescription drugs, as well as herbal supplements) and share it with your doctor and pharmacist. Do not start on your own, stopping it suddenly, or change the dosage of any medications without first consulting your doctor.
  • Missed Dose:

  • If you forget to take one dose, take it as soon as you remember, skip the missed dose and proceed with your daily schedule. To cope up with a missed dose, do not take a double dose.
  • Overdose:

  • Overdose of a drug can be accidental. If you have taken more than the prescribed tablets there is a chance of getting harmful effects on your body’s functions.
  • Storage:

  • Direct contact with heat, air, and light may damage your medicines. Exposure to medicine may cause some harmful effects. The medicine must be kept in a safe place and out of children’s reach.
  • Lidocaine vs Bupivacaine:

    Lidocaine, also known as lignocaine, is an amino amide-type local anesthetic. Bupivacaine is a prescription medication that is used to provide a local anaesthetic (numbing medicine). Bupivacaine is marketed under several brand names, including Marcaine and Sensorcaine
    This medication is applied to the skin to relieve itching and pain caused by certain skin conditions as well as to treat minor discomfort and itching caused by hemorrhoids and other genital problems It is used to reduce sensation in a specific area. In nerve blocks, it is injected around a nerve that supplies the area or into the epidural space of the spinal canal.
    They function by preventing nerves from sending pain signals to the brain. As a result, they cause temporary numbness in the area where they are applied (a "local" anesthetic). Bupivacaine works by blocking nerve impulses that send pain signals to the brain

    Frequently Asked Questions:

    Lidocaine is a local anaesthetic that is used to numb an area of your body in order to reduce pain or discomfort caused by invasive medical procedures such as surgery, needle punctures, or catheter or breathing tube insertion.
    Lidocaine relieves burning and aching pain as well as irritation caused by overly sensitive skin areas. Lidocaine is a type of drug known as a local anaesthetic. It works by causing a temporary loss of sensation in the area where the patch is applied.
    Several studies have reported side effects of lidocaine, which are known to occur during intravascular injection or overdosage. However, side effects such as psychotic reactions, especially euphoria, have been reported infrequently. We present rare case of lidocaine-induced euphoria following an ESPB.
    According to the reviewed literature, lidocaine has anti-inflammatory properties.
    Drowsiness after lidocaine administration is usually an early sign of a high blood level of the drug and may occur as a result of rapid absorption.
    Lidocaine skin cream works quickly, taking effect in 30 to 60 minutes. Use the cream only on healthy skin. It should not be applied to cuts or grazes. Itching and tingling are the most common side effects.
    Lidocaine, like cocaine, is a local anaesthetic with strong sodium-channel blocking properties. Unlike cocaine, lidocaine has no rewarding or addictive properties and has no activity at monoamine re-uptake transporters.
    Yes, it is a local anaesthetic that is also sometimes used for treating neuropathic pain on the skin.
    Lidocaine, a local anaesthetic, works by temporarily numbing the skin. Topical lidocaine is generally safe when used sparingly and as directed. Misuse, overuse, or overdose can result in serious consequences, including death.
    If you have nerve-related chronic back pain, your doctor may prescribe Lidoderm patches in addition to other medications (such as an anticonvulsant or antidepressant) to help you manage your pain and improve your daily function.


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