What is Levocetirizine?

Levocetirizine is an antihistamine used for the treatment of allergic rhinitis and long-term hives of unknown causes, marketed under the brand name Xyzal, among others. It is less sedative than antihistamines which are older. It is swallowed by mouth. Sleepiness, dry mouth, cough, vomiting, and diarrhea are common side effects.

Levocetirizine uses

Levocetirizine is an antihistamine that is used for alleviating symptoms of some allergies, such as watery eyes, runny nose, eye/nose itching, and sneezing. It is sometimes used to alleviate hives and scratching. It works by blocking a certain natural substance that your body produces during an allergic reaction (histamine).

Levocetirizine does not deter or prevent or treat extreme allergic reactions (such as anaphylaxis). Always bring your epinephrine injector with you if your doctor has prescribed epinephrine to treat allergic reactions. In place of epinephrine, do not try to use levocetirizine.

How to use Levocetirizine Dihydrochloride

  • Before taking this drug, read and follow all instructions on the product label if you are taking the over-the-counter product for self-treatment. Consult your pharmacist/doctor if you have any queries. If this drug has been prescribed by your doctor, take it as instructed.
  • This medicine is taken by mouth in the evening, with or without food, usually once a day.
  • Carefully evaluate the dosage using a special measuring device/spoon if you are using the liquid form of this drug. Do not use a household spoon, since the correct dosage can not be given to you by household spoons.
  • The dose will be dependent on your age, medical condition, and treatment response. Do not raise the dosage or take this drug more often than directed.

Levocetirizine Side Effects

  • Dry mouth
  • Fatigue
  • Runny Or Stuffy Nose
  • Sore Throat
  • Central Nervous System Depression
  • Drowsiness
  • Sedation
  • Dizziness
  • Mental Or Physical Weariness
  • Disturbed Coordination
  • Restlessness
  • Inability To Sleep (Insomnia)
  • Shakiness (Tremors)
  • Intense Excitement
  • Nervousness
  • The Disturbed State Of Mind
  • Irregular Heartbeat
  • Seizures
  • Upper Abdominal Distress
  • Loss Of Appetite
  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Impaired Bile Flow (Cholestasis)
  • Inflammation Of The Liver (Hepatitis)
  • Liver Failure
  • Liver Function Abnormality
  • Fast Heart Rate
  • Ecg Changes
  • Abnormal Heart Rhythm (Extra Heartbeat, Heart Block)
  • Low Blood Pressure
  • High Blood Pressure (Hypertension)
  • Difficult Or Painful Urination
  • Urinary Retention
  • Impotence
  • Spinning Sensation (Vertigo)
  • Visual Disturbances
  • Blurred Vision
  • Double Vision
  • Ringing In The Ears (Tinnitus)
  • Acute Inflammation Of The Inner Ear
  • Irritability
  • Involuntary Movement Of Facial Muscles
  • The Tightness Of The Chest
  • Thickening Of Bronchial Secretions
  • Wheezing
  • Sweating
  • Chills
  • Early Menses
  • Toxic Psychosis
  • Headache
  • Faintness
  • Numbness And Tingling
  • Lowered White Blood Cell Count
  • Low Red Blood Cell Count
  • Deficiency Of Platelets


Tell your doctor or pharmacist whether you are allergic to levocetirizine or to cetirizine or hydroxyzine or if you have any other allergies before taking levocetirizine. There might be or maybe inactive ingredients in this substance that may cause allergic reactions or other problems.

Tell your doctor or pharmacist your medical history before taking this drug, particularly: trouble urinating (such as due to enlarged prostate gland ), kidney disease.

You can get drowsy with this medication. You may become more drowsy with alcohol or marijuana (cannabis). Do not do the driving, use big machinery tools, or do something that involves caution before you can do it safely. Stop alcoholic drinks.

Sugar and/or aspartame may be found in liquid goods. If you have diabetes, phenylketonuria (PKU), or some other disease in your diet that allows you to limit/avoid these substances, caution is recommended. Tell your doctor or pharmacist to safely use this drug.

Tell your doctor or dentist of all the medications you use before getting an operation (including prescription drugs, nonprescription drugs, and herbal products).

This drug should be used during pregnancy only when it is specifically needed. Please address with your doctor the risks and benefits.

This medicine is transmitted to breast milk. Before you breast-feed, consult your doctor.


Drug interactions can change the functioning of your drugs or increase your risk of serious side effects. Not all potential interactions with drugs are included in this paper. Keep a list and share it with your doctor and pharmacist of all the drugs you use (including prescription/nonprescription medications and herbal products). Without the consent of your doctor, do not start, stop, or adjust the dosage of any drug.

Consult your doctor if you are taking any other drugs that could induce drowsiness, such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, cannabis, sleep or anxiety pills (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or any other antihistamines (such as diphenhydramine, promethazine).

Check all of your drugs for labels (such as allergy or cough-and-cold products) because they can contain drowsiness-causing ingredients.

Do not use any other skin-applied antihistamines (such as diphenhydramine cream, ointment, spray) because there may be increased side effects.

Levocetirizine is somewhat similar to hydroxyzine and cetirizine. Do not use these drugs when levocetirizine is being used.

Certain laboratory tests (including allergic skin testing) can interfere with this drug, probably causing false test results. Ensure that all of the lab staff and all of your physicians know that you are taking this medicine.

Missed Dose

If you have forgotten to take any doses, take it as soon as you recall. If the time for the next dose has already come, skip the forgotten dose.


Do not overdose. If someone takes too much something serious can happen, immediately go to the doctor.


Keep this drug securely locked with a tight bottle cap/container, and out of the reach of children. Store it away from excess heat/direct heat and moisture at room temperature and (not in the bathroom).

Unneeded drugs should be disposed of in special ways to ensure that they can not be ingested by pets, infants, and other individuals. Do not flush this drug down the toilet or drainage system. Instead, with a prescription take-back service, the safest way to dispose of your medication is. To learn about take-back services in your neighborhood, speak to your pharmacist or contact your local garbage/recycling department.

Levocetirizine vs Cetirizine

Levocetirizine Cetirizine
Molar mass: 388.8878 g/mol Molar mass: 388.89 g/mol
brand name Xyzal brand name Zyrtec
used for the treatment of allergic rhinitis and long term hives of unclear cause used to treat dermatitis, allergic rhinitis, and urticaria.

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Frequently Asked Questions

Is levocetirizine an antibiotic?

Levocetirizine is an antihistamine that decreases the effects of histamine, a natural chemical in the body. Symptoms like a runny nose or hives may be caused by histamine. Levocetirizine is used in children who are at least 6 months old to relieve symptoms of year-round (perennial) allergies.

What are the side effects of levocetirizine?

Some common side effects are dry mouth, fatigue, runny or stuffy nose, sore throat, central nervous system depression, drowsiness, sedation

Can I take levocetirizine twice a day?

The prescribed dosage is 5 mg (1 tablet) of Levocetirizine dihydrochloride tablets once a day in the evening. In certain patients, 2.5 mg (1/2 tablet) once a day in the evening can be adequately monitored. The prescribed dosage is 2.5 mg (1/2 tablet) of Levocetirizine dihydrochloride tablets once a day in the evening.

What is the difference between cetirizine and levocetirizine?

Previous research has shown that levocetirizine is less sedative than cetirizine and that it is equal to 5 mg of cetirizine with 2.5 mg of levocetirizine. The R-enantiomer of cetirizine is levocetirizine, and the researchers thought it would be more potent.

Can levocetirizine make you sleepy?

Levocetirizine is referred to as a non-drowsy antihistamine; in a few individuals, however, it can still induce drowsiness. Before you drive and before you use equipment or machines, ensure that your reactions are natural.

Is levocetirizine a steroid?

Levocetirizine is used to alleviate the symptoms of skin rashes and hay fever. It is an antihistamine that acts by blocking the effects of a compound that the body produces, called histamine. Itching, sneezing, runny nose, and watery eyes can be caused by histamine.

Can levocetirizine be used for cold?

In the treatment of common cold symptoms, Levocetirizine+Phenylephrine+Paracetamol is used. A mixture of three drugs is Levocetirizine + Phenylephrine + Paracetamol: Levocetirizine, Phenylephrine, and Paracetamol, which relieves common cold symptoms.

Does levocetirizine make you gain weight?

People who use Xyzal (levocetirizine)-and antihistamine similar to Zyrtec (cetirizine)-have found that they have put on extra pounds, which is what has been experienced by a very small number of patients who used the medication during studies.

Can I take levocetirizine and paracetamol together?

In the treatment of Common Cold and Allergic Rhinitis in infants, a fixed-dose combination of Paracetamol, Phenylephrine, and Levocetirizine is safe and effective.

Is levocetirizine good for the sinus?

Anti-allergy drugs, such as antihistamines, can be prescribed if allergies are the source of chronic sinusitis. Agents such as Levocetirizine contain these.

Can levocetirizine be taken during pregnancy?

Pregnancy Group B drugs are also new antihistamines, such as over-the-counter loratadine (Claritin, generic forms) and cetirizine (Zyrtec, generic forms). Xyzal is a newer prescription antihistamine that is pregnancy category B. (levocetirizine)

How safe is Levocetirizine?

Yes, many researches and studies that have been conducted have demonstrated levocetirizine to be safe.

Is it safe to take levocetirizine every day?

The prescribed dosage is 2.5 mg (1/2 tablet) of Levocetirizine dihydrochloride tablets once a day in the evening. The dosage of 2.5 mg should not be exceeded because the systemic exposure of 5 mg is around twice that of adults.

Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

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