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Dicyclomine Hydrochloride

Dicyclomine Hydrochloride

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By Medicover Hospitals / 16 Feb 2021
Home | Medicine | Dicyclomine Hydrochloride

What is Dicyclomine Hydrochloride

  • Dicyclomine oral tablet is a prescription medicine. It's available as a brand-name Bentyl drug. It is available as a generic drug. Generic drugs usually cost less than that.. Dicyclomine also comes as a capsule or solution that you take by mouth and by injection. The injection is given only by a health care provider in a clinic.
  • Forms and strengths:
  • Generic name- Dicyclomine
  • Form - Oral tablet
  • Strengths- 20 mg
  • Brand name - Bentyl
    1. Dicyclomine Hydrochloride Uses
    2. Side effects
    3. Precautions
    4. Dicyclomine Hydrochloride vs Drotaverine
    5. FAQ's

    Dicyclomine Hydrochloride Uses:

  • Dicyclomine is used to treat symptoms such as stomach spasms caused by intestinal disorders, including irritable bowel syndrome. It might be used as a part of combination therapy. This means that you may need to take it with other medications.
  • How it works

  • Dicyclomine is a class of drugs called anticholinergics. Classification of drugs that work in a similar way. These drugs are often used for the treatment of similar conditions.
  • This drug affects specific muscles in your stomach and intestines that are called smooth muscles. It helps to relax these muscles in order to relieve the spasms caused by functional intestinal disorders in this part of your digestive system.
  • Dicyclomine Hydrochloride Side Effects:

    • Dry mouth
    • Dizziness
    • Blurry vision
    • Nausea
    • Sleepiness
    • Weakness
    • Nervousness
    • Abnormal or rapid heart rate
  • Eye problems. Symptoms can include:
    • Blurry vision
    • Difficulty moving your eyes
    • Sensitivity to light
    • Allergic reactions
    • Swelling of your face, tongue, throat, arms, and legs
    • Trouble breathing or swallowing
    • Skin rash
    • Welts
    • Hives
    • Temporary episodes of memory loss
    • Irritation
    • Confusion
    • Delusions
    • Disorientation
    • Hallucinations
    • Sudden mood or behaviour changes
    • Decreased breast milk production in breastfeeding women
    • Skin problems
    • Redness
    • Rash
    • Inflammation of your skin

    Precautions:

    • For people with heart problems - Dicyclomine can cause a rapid or abnormal heart rate. The risk of this side effect is increased if you already have an abnormal or rapid heart rate, congestive heart failure, a history of heart attack, or uncontrolled blood pressure.
    • For people with myasthenia gravis- Myasthenia gravis is a disease of muscle weakness. If you have this disease and take dicyclomine, your illness may get worse. High doses of this drug may even cause paralysis in people with this disease. You're not supposed to use this drug if you have myasthenia gravis.
    • For people with intestinal obstruction - Dicyclomine may cause or worsen blockage or obstruction of the digestive tract. If you have removed a portion of your intestine (ileostomy or colostomy), you are at greater risk of this side effect.
    • For people with ulcerative colitis - Dicyclomine can reduce the movement of the digestive tract. If you have ulcerative colitis and take this medicine, the movement of your digestive tract may be slowed to the point where it can cause a condition called toxic megacolon. Symptoms of toxic megacolon include stomach pain, bloating, rapid heart rate, fever, severe diarrhea, and bloody diarrhea. If you have severe ulcerative colitis, you should not take this medicine.
    • For men with enlarged prostate - the use of this drug may cause urinary retention. This can make it hard for you to urinate. If you have an enlarged prostate, you are at an increased risk of this side effect if you take this medicine.
    • For people with liver disease - your body may not be able to treat this medicine as well as it should if you have liver disease. Taking normal doses of this medicine may cause it to build up in your body and increase your risk of side effects. Talk to your doctor before taking this medicine if you have liver disease.
    • For people with kidney disease- your body may not be able to get rid of this medicine as well as it should if you have kidney disease. Taking normal doses of this medicine may cause it to build up in your body and increase your risk of side effects. Talk to your doctor before taking this medicine if you have kidney disease.
    • For people with glaucoma- This drug may increase the pressure in your eyes. If you have glaucoma, this increase in pressure may be harmful to your eyes. You should not use this medicine if you have glaucoma or are taking medicines to treat glaucoma. For people with food poisoning: if you have food poisoning caused by the bacterium of Salmonella, taking dicyclomine may cause serious damage to the low level of toxicity.
    • Dicyclomine is a category B pregnancy drug for pregnant women. It means two things:
      • - Animal research has shown no risk to the fetus when the mother takes the drug.
      • - There are not enough human studies to show whether the drug poses a risk to the fetus.
    • Talk to your doctor if you are in pregnancy or planning to become pregnant. Animal studies do not always predict how the human body would respond. Therefore, this drug should only be used during pregnancy if it is clearly needed. Call your doctor right away if you become pregnant while taking this medicine.
    • For women who are breast-feeding - Dicyclomine should not be used in women who are breast-feeding. Dicyclomine may pass into breast milk and may cause side effects in infants who are breastfed. This drug may also lower the amount of breast milk your body makes. Talk to your doctor if you breastfeed with your child. You may need to decide whether to stop breastfeeding or stop taking this medicine.
    • For the elderly - the kidneys of older adults may not work as well as they used to. This can make your body process drugs more slowly. As a result, more drugs stay in your body for a longer period of time. This might increase your risk of side effects
    • For children- this drug has not been evaluated in children. It should not be used in people younger than 18 years of age.

    Dicyclomine Hydrochloride vs Drotaverine

    Dicyclomine Hydrochloride
    Drotaverine
    Brand Name: Bentyl, Dibent, Dicyclocot Trade name: No-Spa, Doverin
    It is available as Anticholinergic Agents Drotaverine is an antispasmodic drug
    Dicyclomine is used to treat symptoms such as stomach spasms caused by intestinal disorders, including irritable bowel syndrome. Drotaverine is used to enhance cervical dilation during childbirth.
    Formula C19H36ClNO2 Formula: C24H31NO4

    Frequently Asked Questions:

    Dicyclomine is used for the treatment of symptoms of irritable bowel syndrome. Dicyclomine is in a class of drugs that is called anticholinergics. It relieves muscle spasms in the gastrointestinal tract by blocking the activity of a natural substance in the body.
    Dicyclomine is used for relieving colicky pain caused by intestinal muscle spasm in functional bowel/irritable bowel syndrome. Side effects include dry mouth, decreased sweating, nausea, and sedation.
    Dicyclomine oral tablets may cause somnolence. You're not supposed to do anything that requires you to be mentally alert, such as driving or operating machines, until you know how this drug affects you. The drug may also cause many other side effects.
    Do not take this medicine at the same time you take antacids. If you are taking antacid, take it after a meal and take dicyclomine before a meal. The dose is based on your age, medical condition, and response to treatment. Do not increase your dose or take this medicine more often than not without your doctor's approval.
    Stop using dicyclomine when you have stomach pain and call your doctor at once if you have a serious side effect, such as- severe constipation, bloating, stomach pain; worsening of diarrhea or other irritable intestinal symptoms; feeling very thirsty or hot, unable to urinate, heavy sweating, or hot and dry skin.
    It's best to take this medicine on an empty stomach, 30 minutes to 1 hour before meals. Take your medication at regular intervals. Don't take your medicine more often than directed.
    In most cases, these side effects will go away for 12 to 24 hours after the patient stops taking Bentyl. It is important to drink enough water while taking Bentyl, especially during hot weather or during exercise.
    Dicyclomine (Bentyl), for example, is widely used for the treatment of symptoms of irritable bowel syndrome. How they can cause depression: Anticholinergics, as central nervous system depressants, may cause depression, sedation, and cognitive impairment in older patients.
    Other side effects may include loss of appetite, tingling, headache, somnolence, or weakness. Bentyl may also cause more serious side effects, such as confusion or dizziness.

    Citations:

  • Effects of Dicyclomine Hydrochloride, https://jpet.aspetjournals.org/content/146/3/354.short
  • Treatment of the irritable bowel syndrome with Dicyclomine Hydrochloride,https://psycnet.apa.org/record/1995-30502-001