Bleomycin is a cancer care drug. This includes, among others, Hodgkin's lymphoma, non-lymphoma, Hodgkin's testicular, ovarian, and cervical cancer. It can be administered intravenously, by injection into a muscle or under the skin, usually used with other cancer drugs.
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Get A Second OpinionBleomycin is used in cancer care. This drug can also be used to manage the build-up of fluid around the lungs (pleural effusion) caused by tumors that have spread to the lungs. It works by slowing or preventing the growth of cancer cells. Bleomycin is inserted in the space around the lungs through a chest tube for this disease.
This drug is administered by injection into a vein, muscle, or under the skin by a medical professional, usually once or twice a week or as prescribed by your doctor. This drug is injected steadily over a duration of 10 minutes when it is administered into a vein. If you feel some chest pain, inform your health care provider right away. There may be a need to pause or inject the drug more slowly. The dose depends on your medical condition, body size and treatment reaction.
If this drug is administered into the space around the lungs through a chest tube, the solution is usually left in place for 4 hours and then drained out through the chest tube. To ensure the solution treats all parts of your lungs, your doctor may instruct you to change positions during the 4-hour period.
Laboratory and medical tests, such as kidney and liver function tests, complete blood count, blood mineral levels, and hearing tests, should be performed while you are using this medicine. Be sure to keep all medical and laboratory appointments.
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Book an AppointmentIt is important to take each dose of this medicine as scheduled. If you miss a dose, ask your doctor or pharmacist for a new dosing schedule immediately.
Never take more doses than what is preferred. If someone has taken overdoses, immediately take them to the medical emergency.
| Bleomycin | Zeocin |
|---|---|
| Formula - C55H85N17O25S4 | Formula: C55H86N20O21S2 |
| Bleomycin is a medication used for treating cancer. | A glycopeptide antibiotic |
| This drug can also be used to manage the build-up of fluid around the lungs (pleural effusion) caused by tumors that have spread to the lungs. | Is effective against most bacteria, filamentous fungi |
| Molecular Weight 1512.6 g/mol | Molecular Weight 1427.5 g/mol |
Injection site reactions (pressure, redness, warmth, itching, or swelling), fever, chills, vomiting, loss of appetite, weight loss, darkening or discoloration of the skin, changes in the fingernails or toenails, itching, or pain near the tumor are typical side effects of Blenoxane (bleomycin sulfate).
An interstitial oedema with an explosion of inflammatory and immune cells is part of the lung injury seen after bleomycin. This can contribute to the development of pulmonary fibrosis, characterized by increased collagen production and deposition and other components of the matrix.
Bleomycin is used in cancer care. This drug can also be used to manage the build-up of fluid around the lungs (pleural effusion) caused by tumors that have spread to the lungs. It works by slowing or preventing the growth of cancer cells. Bleomycin is inserted in the space around the lungs through a chest tube for this disease.
In some people, Bleomycin can cause temporary hair loss. Natural hair growth should return after treatment has finished, but it may take many months. If you smoke, side effects that damage your lungs (such as coughing and shortness of breath) may be more likely to occur.
By modulating fibroblast proliferation via a TGF- response, bleomycin can upregulate collagen synthesis. Extreme, permanent pulmonary fibrosis can result from excessive collagen deposition.
Intramuscular, subcutaneous, intravenous, intrapleural, intralesional, or intra arterial bleomycin is administered. Acetaminophen pre-medication can decrease the incidence of fever and chills following administration of bleomycin.
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