Onychomatricoma - Symptoms, Reasons and Treatment

Onychomatricoma is a rare and benign tumor that develops in the nail matrix, which is the tissue responsible for producing the nail plate. This condition causes overgrowth of the nail matrix, leading to the formation of a tumor-like mass within the nail. The exact cause of onychomatricoma is not fully understood, but it is believed to be related to trauma or injury to the nail matrix. 

While this condition is not harmful, it can cause changes in the appearance and texture of the affected nail. If you notice any unusual growth or changes in your nails, it is essential to consult a healthcare provider for proper evaluation and management.

Symptoms of Onychomatricoma

Symptoms may include a thickened or discolored nail, pain, and nail deformity. In some cases, the affected nail may grow more slowly than usual. If you observe any of these symptoms, it's essential to consult a healthcare provider for an accurate diagnosis and appropriate management.

  • Onychomatricoma may present as a thickened or distorted toenail, resembling a tumor under the nail plate.
  • Some individuals with onychomatricoma may experience pain or discomfort in the affected toe.
  • The affected nail in onychomatricoma can have a yellowish or brownish discoloration, often with irregular borders.
  • Onychomatricoma can cause nail splitting or lifting, leading to potential secondary infections or nail deformities.
  • In advanced cases, onychomatricoma may exhibit bleeding or discharge from the affected nail bed.

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Causes of Onychomatricoma

Prolonged pressure or repetitive microtrauma may contribute to the development of onychomatricoma. Early detection and proper diagnosis are crucial for effective management of this condition. If you notice any unusual changes in your nails, it's essential to consult a healthcare professional for evaluation and appropriate treatment.

  • Onychomatricoma may result from chronic trauma or repeated injury to the nail matrix, leading to the development of this rare benign tumor.
  • Genetic predisposition or familial history of onychomatricoma may contribute to its occurrence in some individuals.
  • Underlying inflammatory skin conditions such as psoriasis or lichen planus can be associated with the development of onychomatricoma.
  • Long-term use of certain medications or exposure to chemicals known to affect nail health may increase the risk of developing onychomatricoma.
  • In rare cases, onychomatricoma may be linked to systemic diseases like diabetes or autoimmune disorders, impacting nail matrix function and leading to tumor formation.

Types Of Onychomatricoma

Types of onychomatricoma may include classic onychomatricoma characterized by a longitudinal groove on the nail plate, pincer nail-like onychomatricoma with lateral nail plate thickening, and subungual keratotic tumors resembling a verruca. These distinctive types of onychomatricoma showcase the diverse clinical presentations of this uncommon nail tumor.

  • Onychomatricoma is a rare benign tumor of the nail matrix.
  • Types of onychomatricoma include typical, subungual keratotic, and onychomatricoma-like tumors.
  • Typical onychomatricomas present as a solitary nodule beneath the nail plate.
  • Subungual keratotic onychomatricomas exhibit a thickened nail plate with a central area of keratin accumulation.
  • Onychomatricoma-like tumors resemble onychomatricomas but lack connection to the nail matrix.
  • Accurate diagnosis of onychomatricoma is crucial for appropriate management.
  • Surgical excision is the primary treatment for onychomatricoma to prevent recurrence.

Risk Factors

Onychomatricoma is associated with several risk factors. Chronic trauma or repeated injury to the nail bed, such as from occupational activities or sports, can predispose individuals to developing this condition. Additionally, individuals with a history of nail disorders, such as onycholysis or chronic paronychia, may have an increased risk of developing onychomatricoma. Regular monitoring and prompt evaluation of any changes in the nails are essential for early detection and management of onychomatricoma.

  • Prolonged or repeated trauma to the nails can increase the risk of developing Onychomatricoma.
  • Individuals with a history of nail infections or chronic nail bed inflammation may have a higher likelihood of Onychomatricoma.
  • Poor nail hygiene practices, such as inadequate trimming or cleaning, may contribute to the development of Onychomatricoma.
  • Certain medical conditions, like psoriasis or fungal infections, can predispose individuals to Onychomatricoma.

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Diagnosis of Onychomatricoma

Diagnosing onychomatricoma typically involves a comprehensive assessment that includes clinical examination, nail dermoscopy, and histopathological evaluation of nail biopsy samples.  However, the definitive diagnosis of onychomatricoma is established through histopathological analysis, which involves examining the tissue under a microscope for specific pathological changes unique to this condition.

  • Dermoscopy can aid in identifying specific patterns such as irregular vessels and yellowish areas within the lesion.
  • Histopathological examination through nail plate biopsy is often necessary for definitive diagnosis of Onychomatricoma.
  • Imaging studies like ultrasound or magnetic resonance imaging (MRI) may be used to assess the extent of nail bed involvement.
  • Differential diagnosis includes other nail tumors and benign conditions like onychomycosis, making accurate diagnostic methods crucial.

Treatment for Onychomatricoma

Onychomatricoma, typically requires surgical intervention for treatment. The primary approach involves complete excision of the lesion to prevent recurrence and alleviate symptoms. Depending on the size and extent of the tumor, the surgical procedure may range from a simple excision to more extensive nail unit surgery. 

In some cases, a biopsy may be performed to confirm the diagnosis before proceeding with treatment. Post-operatively, proper wound care and monitoring are essential to ensure optimal healing and reduce the risk of complications.

Regular follow-up appointments are essential to monitor the healing process and assess for any signs of recurrence. In situations where the lesion is extensive or shows aggressive behavior, more advanced treatments like Mohs micrographic surgery or laser therapy

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Frequently Asked Questions

Are there specific signs that indicate Onychomatricoma?

Onychomatricoma can show as a thickened, discolored nail with a characteristic longitudinal split or groove.

Are there specific things I should or shouldn't do when dealing with Onychomatricoma?

Avoid self-treatment and seek a dermatologist for proper diagnosis and treatment of Onychomatricoma.

What are the potential complications of Onychomatricoma?

Potential complications of Onychomatricoma include nail deformities, pain, infection, and recurrence after surgical removal.

How can Onychomatricoma be treated and controlled?

Onychomatricoma can be treated with surgical removal. Regular follow-ups are needed to monitor for recurrence and ensure proper healing.

What are the chances of Onychomatricoma recurring?

Onychomatricoma recurrence is rare after complete removal.

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