Herpetic Keratitis: Signs, Causes, And How To Treat

Herpetic keratitis is a viral infection affecting the eye caused by the herpes simplex virus. This condition can lead to discomfort and potential complications if left untreated. It is important to seek prompt medical attention if you suspect you have herpetic keratitis. 

By understanding the causes and risk factors associated with this condition, you can take steps to protect your eye health and prevent future flare-ups. Remember to consult with an eye care professional for proper diagnosis and treatment tailored to your specific needs.

What Are the Symptoms of Herpetic Keratitis

In severe cases, it may lead to vision loss.  If you experience any of these symptoms, especially if you have a history of cold sores or herpes, seek immediate medical attention to prevent complications.

  • Redness and irritation in the eye, often accompanied by a gritty sensation, can be a symptom of herpetic keratitis.
  • Watery eyes that are sensitive to light and may experience blurred vision are common signs of herpetic keratitis.
  • Feeling like something is in your eye or experiencing increased tearing can be indicative of herpetic keratitis.
  • Pain or discomfort in the eye that worsens with blinking or exposure to light may be a symptom of herpetic keratitis.
  • Developing sores on or around the eye, along with eye redness and swelling, could be a sign of herpetic keratitis.

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Causes of Herpetic Keratitis

The virus typically enters the eye through direct contact with a contaminated source, such as a cold sore or genital herpes lesion. Other risk factors include compromised immune function, trauma to the eye, and stress.

  • Herpetic keratitis can be caused by the herpes simplex virus type 1 (HSV-1) entering the eye through direct contact with an active lesion on the face or mouth.
  • Individuals who have a history of cold sores or genital herpes caused by HSV-1 or HSV-2 are at an increased risk of developing herpetic keratitis.
  • Contact with contaminated objects such as towels, makeup brushes, or contact lenses that have come into contact with the herpes virus can lead to herpetic keratitis.
  • People with a weakened immune system due to conditions like HIV/AIDS, cancer, or undergoing immunosuppressive therapy are more susceptible to developing herpetic keratitis.

Types Of Herpetic Keratitis

There are two main types of herpetic keratitis: epithelial and stromal. Epithelial herpetic keratitis affects the outer layer of the cornea, causing symptoms like redness, pain, and blurred vision. 

Stromal herpetic keratitis involves the deeper layers of the cornea and can lead to scarring and vision loss if left untreated. Both types are caused by the herpes simplex virus and require prompt medical attention.

  • Epithelial keratitis is a common form of herpetic keratitis that affects the outermost layer of the cornea, causing symptoms such as eye redness, tearing, and sensitivity to light.
  • Stromal keratitis is a more serious type of herpetic keratitis that can lead to scarring of the cornea, resulting in vision impairment if left untreated.
  • Endothelial keratitis is a rare form of herpetic keratitis that affects the innermost layer of the cornea, leading to swelling and clouding of the cornea, which can affect vision clarity.

Risk Factors

Risk factors for herpetic keratitis include a history of cold sores, compromised immune system, contact lens use, eye trauma, and stress. Environmental factors like UV light exposure and smoking can also increase the risk. 

Proper hygiene practices, avoiding sharing personal items, and managing stress levels can help reduce the likelihood of developing herpetic keratitis.

  • Individuals with a history of herpes simplex virus (HSV) infection are at increased risk for herpetic keratitis.
  • Using contact lenses, especially when not properly cleaned or stored, can elevate the risk of developing herpetic keratitis.
  • People who have had corneal trauma or injury are more susceptible to developing herpetic keratitis.
  • Patients with compromised immune systems, such as those with HIV/AIDS or undergoing immunosuppressive therapy, have a higher risk of herpetic keratitis.
  • Prolonged exposure to ultraviolet (UV) radiation, such as from sunlight or tanning beds, can increase the likelihood of developing herpetic keratitis.

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Diagnosis of Herpetic Keratitis

To diagnose herpetic keratitis, your eye doctor will examine your eyes using a special microscope to check for signs of the infection. They may also take a sample of the eye fluid for testing. 

Symptoms like eye redness, pain, and sensitivity to light will also be considered. Early diagnosis is important for prompt treatment and to prevent complications.

  • Slit-lamp examination is a primary diagnostic method for herpetic keratitis, allowing the ophthalmologist to visualize characteristic lesions on the cornea.
  • Viral culture of corneal scrapings can be performed to isolate and identify the herpes simplex virus (HSV) responsible for the infection.
  • Polymerase chain reaction (PCR) testing is a highly sensitive technique that can detect the genetic material of HSV in ocular samples, aiding in the definitive diagnosis of herpetic keratitis.
  • Fluorescein staining of the cornea under cobalt blue light can reveal classic dendritic ulcers, a hallmark sign of herpetic keratitis.

Treatment for Herpetic Keratitis

Treatment for herpetic keratitis typically involves antiviral eye drops or ointments to help control the viral infection. In more severe cases, oral antiviral medications may be prescribed. 

Additionally, your eye doctor may recommend steroid eye drops to reduce inflammation and promote healing. It is important to follow your doctor's instructions carefully and attend regular follow-up appointments to monitor your progress and ensure proper management of the condition.

  • Antiviral eye drops, such as acyclovir or ganciclovir, are commonly prescribed to help reduce the viral replication in herpetic keratitis and alleviate symptoms.
  • Topical corticosteroids may be used in combination with antiviral therapy to reduce inflammation and prevent scarring in more severe cases of herpetic keratitis.
  • Debridement, a procedure where the affected corneal tissue is removed, may be necessary in cases of persistent epithelial defects or necrotizing herpetic keratitis.
  • Oral antiviral medications, like valacyclovir or famciclovir, may be recommended for severe or recurrent cases of herpetic keratitis to help reduce the severity and frequency of outbreaks by targeting the underlying viral infection.
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Frequently Asked Questions

How do I recognize the signs of herpetic keratitis?

Signs of herpetic keratitis include eye pain, redness, light sensitivity, blurred vision, and feeling like something is in your eye.

How should I care for myself with herpetic keratitis—what should I do and avoid?

Protect your eyes from sunlight and wear sunglasses. Avoid touching your eyes, sharing towels, and contact lenses. Follow treatment as prescribed by the doctor.

Can herpetic keratitis lead to other health issues?

Herpetic keratitis can lead to serious eye complications like scarring, vision loss, and in severe cases, may result in blindness.

How is herpetic keratitis typically managed?

Herpetic keratitis is managed with antiviral eye drops or ointments, steroid eye drops for inflammation, and in severe cases, oral antiviral medications.

Can herpetic keratitis return even after successful treatment?

Yes, herpetic keratitis can recur even after successful treatment due to the dormant nature of the herpes simplex virus in the body.

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