Esophagitis: Types, Symptoms, Causes and Treatment
Written by Medicover Team and Medically Reviewed by Dr Santosh M Narayankar , Gastroenterologists
Esophagitis is a condition where the lining of the esophagus becomes inflamed or irritated. The esophagus is the muscular tube that carries food and liquids from your mouth to your stomach.
When this lining becomes swollen or damaged, it can cause pain, especially when swallowing. People with esophagitis may feel a burning sensation in the chest, discomfort while eating, or even food getting stuck.
This condition can result from acid reflux, infections, certain medications, or allergic reactions. Prompt diagnosis and treatment are important to avoid complications like scarring or narrowing of the esophagus.
What Is Esophagitis?
Esophagitis (pronounced uh-sof-uh-JY-tis) means inflammation of the esophagus, the tube that connects your throat to your stomach.
The inflammation happens when the tissue lining the esophagus becomes irritated, swollen, or damaged. This can be caused by:
- Stomach acid flowing back into the esophagus (acid reflux or GERD)
- Infections (bacterial, viral, or fungal)
- Oral medications that irritate the lining
- Allergic reactions (e.g., eosinophilic esophagitis)
Common symptoms include:
- Pain or difficulty when swallowing
- Chest pain, especially behind the breastbone
- A feeling that food is stuck in the throat
If left untreated, esophagitis can lead to more serious issues like ulcers, strictures (narrowing of the esophagus), and long-term swallowing problems.
What Are the Different Types of Esophagitis?
Esophagitis can be caused by many different things, so doctors divide it into several types based on the cause. Some types happen when stomach acid flows back into the esophagus. Others are caused by allergies, infections, certain medications, or cancer treatments like radiation.
Each type affects the esophagus in a different way and may need a different kind of treatment. Knowing the type of esophagitis you have can help your doctor choose the best way to treat it and prevent future problems.
Below are the main types of esophagitis, explained in simple terms to help you understand what’s going on and how it can be managed.
Reflux Esophagitis
This is the most common type. It happens when stomach acid flows backward into the esophagus. This is often caused by a condition called GERD (gastroesophageal reflux disease).
Over time, the acid irritates and damages the lining of your esophagus, causing pain, heartburn, and trouble swallowing. Other causes can include bile reflux or frequent vomiting.
Eosinophilic Esophagitis
This type is related to allergies or immune system reactions. It happens when a type of white blood cell called an eosinophil builds up in the esophagus and causes swelling.
It’s more common in people with food allergies, asthma, eczema, or hay fever. Common triggers include:
- Milk
- Eggs
- Wheat
- Soy
- Peanuts
- Tree nuts
- Shellfish
This type is especially seen in children and can make eating difficult or uncomfortable.
Drug-Induced Esophagitis (Pill Esophagitis)
This happens when certain medications irritate the esophagus, especially if not taken with enough water. Pills may get stuck and cause damage to the lining.
Medications that can cause this include:
- Pain relievers (like NSAIDs)
- Antibiotics
- Iron supplements
- Potassium chloride
- Some medications for osteoporosis (bisphosphonates)
Infectious Esophagitis
This is caused by a bacterial, viral, or fungal infection in the esophagus. It’s more common in people with weakened immune systems, such as those with:
- HIV/AIDS
- Cancer
- Diabetes
- Organ transplants
- People taking steroids or chemotherapy
Common infections include:
- Candida (a yeast infection)
- Herpes simplex virus (HSV)
- Cytomegalovirus (CMV)
Radiation Esophagitis
This can happen after radiation therapy to the chest, neck, or throat, especially when used to treat cancer. Radiation can damage the lining of the esophagus, causing pain and swelling. In most cases, the irritation is temporary, but sometimes it can become long-lasting.
Autoimmune Esophagitis
In rare cases, other autoimmune diseases (when the body attacks itself by mistake) can cause inflammation in the esophagus. These include:
- Graft-versus-host disease
- Inflammatory bowel disease (IBD)
- Behcet's disease
What Are the Symptoms of Esophagitis?
The symptoms of esophagitis ulcers can range from mild to severe and may feel different depending on the cause. In most cases, the esophagus becomes sore or irritated, which can make eating or swallowing uncomfortable.
Common Symptoms of Esophagitis in Adults and Teens
Most people with esophagitis notice problems when they eat or swallow. You might feel:
- Difficulty swallowing: It may feel like food is stuck in your throat or chest.
- Painful swallowing: A sharp or burning feeling when you swallow.
- Heartburn: A burning pain in your chest, usually after eating or at night.
- Chest pain: Often felt behind the breastbone, and sometimes mistaken for heart-related pain.
- Acid reflux: When stomach acid comes back up into your throat.
- Sore throat: Especially if the irritation is near the top of the esophagus.
- Feeling full too quickly: You might feel like you can't finish your meals.
- Nausea or vomiting: In some cases, the irritation can cause stomach discomfort or lead to throwing up.
- Regurgitation: When food or sour-tasting liquid unexpectedly comes back up into your mouth.
- Mouth sores: Especially in severe or infectious types of esophagitis.
Severe Symptoms
In more advanced or untreated cases, symptoms can include:
- Food getting stuck: You may feel like food doesn’t go down all the way (called food impaction).
- Bleeding: Blood in vomit or black, tarry stools may be a sign of bleeding in the esophagus.
- Unexplained weight loss: Due to pain or difficulty eating.
- Dehydration: Especially if vomiting or feeding problems continue.
Esophagitis in Babies and Children
Young children can’t always describe how they’re feeling, so signs of esophagitis may look different. Watch for:
- Refusing to eat or drink
- Crying or fussiness during feeding
- Arching the back while feeding- A sign of discomfort or pain
- Choking or gagging during meals
- Poor weight gain or “failure to thrive”
- Ongoing irritability or trouble sleeping
- Belly or chest pain- Older children may be able to point to where it hurts
What Are the Causes of Esophagitis?
Esophagitis occurs when the lining of the esophagus becomes irritated or inflamed. This inflammation can result from a variety of causes, ranging from physical injury to immune system reactions. Identifying the underlying cause is crucial for effective treatment, as esophagitis can present in different forms based on its origin.
Common Causes of Esophagitis
Gastroesophageal Reflux Disease (GERD)
One of the most common causes, GERD, occurs when stomach acid frequently backs up into the esophagus, irritating its lining.
Medications
Some pills can hurt your esophagus, especially if you take them without enough water. Examples include:
- Pain relievers like ibuprofen or aspirin
- Antibiotics like doxycycline
- Iron or potassium supplements
- Osteoporosis medications
Infections
Esophageal infections are more likely in individuals with weakened immune systems. These infections may be caused by:
- Viruses (like herpes or CMV)
- Fungi (like Candida, a yeast infection)
- Bacteria (less common, but possible)
Allergic Reactions (Eosinophilic Esophagitis)
Caused by a reaction to certain foods or allergens. It’s more common in people with asthma, eczema, or seasonal allergies.
Autoimmune Conditions
Rare autoimmune disorders, such as Crohn’s disease or Behçet’s disease, can cause esophageal inflammation.
Physical or Chemical Injury
Injury from ingesting corrosive substances (like cleaning products) or from swallowing large pills can damage the esophageal lining.
Vomiting or Surgery
Frequent or forceful vomiting and complications from esophageal or gastric surgery can also irritate the esophagus.
Radiation Therapy
Patients receiving radiation to the chest or neck (e.g., for cancer treatment) may develop radiation-induced esophagitis.
Hiatal Hernia
A hiatal hernia can exacerbate acid reflux, contributing to esophageal irritation and inflammation.
Get a second opinion from trusted experts and makeconfident, informed decisions.
Get Second OpinionWhat Are the Risk Factors of Esophagitis?
You may be at higher risk for developing esophagitis if you experience any of the following:
- Pregnancy
- Smoking
- Obesity or carrying extra weight
- Frequent consumption of certain foods and drinks, such as alcohol, coffee, chocolate, fatty meals, or spicy foods
- Taking certain medications like NSAIDs (pain relievers), nitrates, or beta blockers
- Radiation treatment to the chest area, often for cancer
- Swallowing medications improperly, such as taking pills without enough water or choking on tablets
- Having scleroderma, a condition that affects the muscles and tissues in the esophagus
- Multiple allergies, especially food allergies
Being aware of these risk factors can help you take precautions and talk to your healthcare provider about ways to reduce your chances of developing esophagitis.
How Is Esophagitis Diagnosed?
To diagnose esophagitis, your healthcare provider will start by asking about your symptoms and medical history. They will also perform a physical exam. If needed, they may order one or more tests to confirm the diagnosis and find out what’s causing the inflammation.
Common Tests Used to Diagnose Esophagitis
Upper Endoscopy
The doctor gently passes a thin, flexible tube with a tiny camera down your throat into your esophagus. This lets them see if your esophagus is irritated or damaged. They may also take small tissue samples (called biopsies) to check under a microscope.
Esophageal Sponge Test
This test is less invasive than an endoscopy. You swallow a small capsule attached to a string. Once it reaches your stomach, the capsule dissolves and releases a sponge. The doctor pulls the sponge back up to collect cells from your esophagus. These cells are tested to check for inflammation or infection.
Barium Swallow X-ray (Upper GI Series)
You drink a special liquid with barium that coats your esophagus. X-rays are taken to look for problems like narrowing, swelling, or other changes.
Laboratory Tests on Biopsy Samples
Tissue samples taken during endoscopy may be sent to a lab to:
- Identify infections caused by bacteria, viruses, or fungi
- Check for allergic inflammation by counting certain immune cells called eosinophils
- Detect abnormal cells that could suggest cancer or precancerous changes
Additional Tests (if needed)
- Esophageal pH monitoring measures acid levels in the esophagus to help diagnose reflux-related esophagitis.
- Other specialized tests may be ordered depending on your symptoms and initial results.
What Are the Treatment Options for Esophagitis?
The treatment you need depends on the cause of your esophagitis. The main goals are to reduce your symptoms, heal the esophagus, and prevent any complications that could affect your eating or overall health.
Your healthcare provider will recommend treatment based on what is irritating or damaging your esophagus. This may involve medications, lifestyle changes, diet adjustments, or sometimes procedures or surgery.
Treatment for Reflux Esophagitis (Caused by Acid Reflux)
- Over-the-counter medicines: Antacids, H2 blockers (like ranitidine), and proton pump inhibitors (PPIs) such as omeprazole help reduce stomach acid and relieve heartburn and inflammation.
- Prescription medicines: Stronger versions of acid-reducing drugs may be prescribed if needed.
- Lifestyle changes: Avoid large or fatty meals, don’t eat right before bedtime, quit smoking, and maintain a healthy weight to reduce acid reflux.
- Surgery: If medicines and lifestyle changes aren’t enough, surgery called fundoplication can strengthen the valve between your stomach and esophagus to prevent acid from backing up.
Treatment for Eosinophilic Esophagitis (Allergy-Related)
- Avoid triggers: Identify and avoid foods or allergens causing your symptoms.
- Medications:
- Proton pump inhibitors reduce acid and inflammation.
- Swallowed steroids (like budesonide or fluticasone) that coat the esophagus and reduce allergic inflammation with fewer side effects than oral steroids.
- Newer options like monoclonal antibodies (e.g., dupilumab) may be used for severe cases.
- Diet plans:
- An elimination diet where you remove common allergens and slowly add foods back to find triggers.
- Elemental diet is a special formula-based diet, guided by your healthcare provider.
Treatment for Medicine-Induced Esophagitis
- Stop or switch the medicine causing irritation when possible.
- Take pills with plenty of water and stay upright for at least 30 minutes after taking them.
- Use liquid medicine forms if available and appropriate.
Treatment for Infectious Esophagitis
Antibiotics, antivirals, or antifungal medications are used depending on whether bacteria, viruses, or fungi are causing the infection.
Treating Complications
If your esophagus becomes very narrow or food gets stuck, your doctor can gently stretch it using special tools during an endoscopy to improve swallowing.
When to See a Esophagitis Doctor?
Esophagitis is the inflammation or irritation of the esophagus, the tube that connects your mouth to your stomach. It can make swallowing painful or difficult and may be caused by acid reflux, infections, medications, or allergies.
You should see a doctor if you experience:
- Pain or difficulty when swallowing
- Chest pain that’s not related to the heart
- Heartburn or acid reflux that doesn’t go away
- A feeling of something stuck in your throat
- Sore throat or hoarseness, especially when eating
- Food coming back up (regurgitation) or vomiting
If symptoms last more than a few days, or if you’re unable to eat or drink properly, seek medical attention. People with weakened immune systems or chronic acid reflux (GERD) are at a higher risk of complications and should not ignore symptoms.
Your health is everything - prioritize your well-being today.
What Are the Complications of Esophagitis?
Esophagitis is usually treatable, especially when caught early. But if it’s left untreated or becomes severe, it can lead to serious health problems. These complications can affect how well you eat, swallow, and even increase your risk for certain long-term conditions.
Here are some possible complications to watch out for:
- Esophageal Ulcers: Ongoing irritation can cause open sores (ulcers) in the lining of your esophagus. These can be painful and may bleed. In rare cases, a deep ulcer can lead to a hole in the esophagus, which is a medical emergency.
- Narrowing of the Esophagus (Stricture): Long-term inflammation can cause scar tissue to form. This scar tissue can make your esophagus narrow, making it harder to swallow food or liquids. You might feel like food is getting stuck in your throat.
- Barrett’s Esophagus: If acid keeps coming up into the esophagus (like with chronic acid reflux), the cells in the lining can change. This condition is called Barrett’s esophagus. It can increase your risk of developing esophageal cancer over time.
- Bleeding: Inflamed or damaged tissue in the esophagus can bleed. This might show up as black or bloody vomit, or dark stools. If you notice this, see a doctor right away.
- Trouble Eating or Drinking: Pain or difficulty swallowing can lead to eating less, which may cause weight loss, malnutrition, or dehydration.
- Tears in the Esophagus: In rare cases, severe vomiting or a medical procedure can cause small tears in the esophagus, especially if it’s already inflamed. This can cause chest pain or bleeding and needs quick medical attention.
What are the Prevention of Esophagitis?
The preventive measures of esophagitis include:
- Dietary and lifestyle modifications may help avoid esophagitis due to GERD.
- Good dental hygiene can prevent candida yeast-induced esophagitis.
- Take all medications upright with lots of water.
Dos and Don’ts In Esophagitis?
If you have esophagitis, eating, drinking, and swallowing can be painful and uncomfortable. While the esophagus often heals on its own, making a few changes to your diet can really help reduce irritation and ease symptoms.
Avoiding certain foods and choosing gentler options gives your esophagus time to heal and makes eating less of a struggle. It also helps prevent food from getting stuck or causing more damage.
Here’s a simple list of do’s and don’ts to help you feel better while your esophagus heals:
|
Do’s |
Don’ts |
|---|---|
|
Stop smoking |
Bend over or lie down after eating |
|
Eat small meals slowly |
Wear tight clothes around your chest and stomach |
|
Lose weight if you are overweight |
Drink alcohol or drinks that have caffeine |
|
Stick to low-fat foods and protein |
Eat deep-fried and spicy foods |
|
Try to avoid eating for 3 hours before bedtime. |
Eat citrus fruits like oranges, lemons, and grapefruits that are acidic and can harm the esophagus. |
Try to avoid eating for 3 hours before bedtime.Eat citrus fruits like oranges, lemons, and grapefruits that are acidic and can harm the esophagus.
The treatment of esophagitis involves taking medicines and adapting to good lifestyle habits. Precautions and self-care will help to fight this condition positively and improve your quality of life.
Our Experience Treating Esophagitis at Medicover
At Medicover, we provide expert care for people experiencing symptoms of esophagitis. Our skilled team of gastroenterologists uses advanced tools to diagnose the cause and create a personalized treatment plan.
We offer:
- Endoscopy and imaging tests to view the esophagus and detect inflammation, damage, or infection
- Acid reflux management, including medications that reduce stomach acid
- Diet and lifestyle guidance to prevent irritation and promote healing
- Treatment for infections or allergies, if they are the cause of the inflammation
- Monitoring and follow-up care to ensure long-term relief and prevent future flare-ups
Whether your symptoms are due to reflux, medication side effects, or another condition, we work with you closely to provide relief and protect your esophagus.
At Medicover, our goal is to ease your discomfort and support your full recovery, so you can eat, drink, and live more comfortably.
