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08-08-2024 Team Medicover general-medicine

Written by Medicover Team and Medically Reviewed by Dr Mithil B Ghushe, General Medicine

Lexapro Uses: Dosage and Treatment

Lexapro, also known by its generic name escitalopram, is a popular medication in the field of mental health. It is primarily used to treat depression and generalised anxiety disorder (GAD).

This article will explore the various uses of Lexapro, what it treats, how it works & when it's prescribed and how it compares to other medications.

What Is Lexapro?

Lexapro is a prescription antidepressant that belongs to a class of medications called Selective Serotonin Reuptake Inhibitors (SSRIs). It is used to treat mental health conditions related to mood and anxiety.

SSRIs like Lexapro work by improving the levels of serotonin, a chemical in the brain that is vey important for mood regulation. When serotonin levels are balanced, people feel more emotionally stable and less anxious.

Overview of Lexapro:

Drug class: SSRI (Selective Serotonin Reuptake Inhibitor)
Generic name: Escitalopram
Common brand name: Lexapro
Type: Prescription medication
Used for: Mental health conditions like depression and anxiety.

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Approved Uses of Lexapro in India

The use of Lexapro in India is largely based on international guidelines like those from the U.S. FDA and NICE UK as well as clinical judgment by Indian doctors.

1. Major Depressive Disorder (MDD)

Lexapro is prescribed to people experiencing moderate to severe depression. It works by improving serotonin levels in the brain, which helps boost mood and emotional stability.

Why it's used: To reduce symptoms like sadness, hopelessness, tiredness or lack of motivation
Who it's for: Adults and sometimes adolescents, based on clinical need
How it helps: Improves emotional well-being, energy levels and daily functioning

2. Generalized Anxiety Disorder (GAD)

Lexapro is also commonly used for people who suffer from excessive worry and anxiety. This condition is known as generalised anxiety disorder (GAD). It helps reduce constant nervousness, physical tension and overthinking.

Why it's used: Helps manage chronic stress, fear and restlessness
Who it's for: Usually prescribed for adults and older teenagers under supervision
How it helps: Promotes calmness, better sleep and reduced physical anxiety symptoms

Common Off-Label Uses of Lexapro

Doctors in India also use Lexapro for several off-label conditions, meaning they are not officially approved for these conditions but the medicine has shown benefit based on clinical experience and research.

Common Lexapro Off-Label Uses in India:

Social Anxiety Disorder (SAD): It is for people who feel extreme fear in social situations
Obsessive-Compulsive Disorder (OCD): It helps reduce repetitive thoughts and behaviors
Panic Disorder: It focuses on helping people who experience sudden panic attacks, which can come with feelings of intense fear.
Post-Traumatic Stress Disorder (PTSD): It is used to help those who have gone through traumatic events and often deal with emotional distress and flashbacks.
Premenstrual Dysphoric Disorder (PMDD) helps with severe mood swings before menstruation.

How Does Lexapro Work?

Lexapro works by increasing the amount of serotonin available in the brain. Serotonin is a chemical messenger that influences mood, sleep and emotional balance.

Blocks serotonin reuptake: Prevents the brain from absorbing serotonin too quickly
Promotes stabilisation: Helps regulate mood and reduce anxiety
Takes time to work: Effects typically begin within 1–4 weeks.

This action helps people feel calmer, more emotionally balanced and better able to manage daily stress.

Lexapro Dosage and Treatment Duration

Typical Lexapro Dosage:

Starting dose: 10 mg per day
Maximum dose: Can go up to 20 mg depending on patient response.

How Long Does Lexapro Take to Work?

Most people start noticing improvement in 1 to 4 weeks
Full effects may take up to 6 to 8 weeks in some cases
Important to take it daily and consistently.

What are the Side Effects of Lexapro?

Lexapro is generally safe but some people may experience side effects, when first starting the medicine or because of improper uses of the medicine.

Common Side Effects:

Nausea: This is one of the most common side effects and usually subsides after a few weeks. Drinking sufficient amount of water and eating small & frequent meals can help mitigate this symptom.

Insomnia: Difficulty sleeping is another common side effect. Making a regular sleep routine and avoiding caffeine can help you improve sleep quality.

Sexual Dysfunction: Some individuals may experience a decrease in libido or difficulty achieving orgasm. Consult with your doctor can help address these issues, possibly through dosage adjustments or additional treatments.

Headache: This is a common initial side effect that usually subsides as your body adjusts to the medication.

Dizziness: Feeling lightheaded can occur, especially when standing up quickly.Staying hydratedand rising slowly can help manage this symptom.

Increased Anxiety: When you first start taking Lexapro, you might feel more anxious than usual. This symptom will heal by its own after your body gets used to the medication.

Serious Side Effects:

Suicidal thoughts: This is a particular concern for young adults under the age of 25. If you experience these thoughts, it's crucial to seek help immediately.
Serotonin syndrome: This is a rare but serious condition that happens when there is too much serotonin in the body. It’s important to be alert for signs of this condition.

Important: Never stop Lexapro suddenly. Always talk to your doctor first, as they will help you gradually reduce the dosage to avoid any withdrawal symptoms.

Who Should Not Take Lexapro?

Lexapro may not be suitable for everyone. Some people should avoid it or use it only under strict medical supervision.

People taking MAO inhibitors can experience dangerous interactions.
Individuals with bipolar disorder may experience manic episodes if not stabilised.
Pregnant or breastfeeding women must consult their doctor.

Always discuss your full medical history with your doctor before starting Lexapro.

Lexapro vs Other SSRIs

Lexapro is often compared to other SSRIs like Zoloft (sertraline) and Prozac (fluoxetine).

Feature	Lexapro	Zoloft	Prozac
Generic name	Escitalopram	Sertraline	Fluoxetine
Onset of effect	1–4 weeks	2–6 weeks	2–6 weeks
Dosing simplicity	Once daily	Once daily	Once daily
Notable distinction	“Cleaner” formulation	More activating	Long half-life

Lexapro is known for its cleaner formulation, meaning it contains only the active part (enantiomer) of the drug, which may lead to fewer side effects.

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Conclusion

Lexapro is a trusted and widely used SSRI that helps many people manage conditions like depression and anxiety. It can also be helpful for several off-label uses but always take it under medical supervision.

If you're considering starting Lexapro, talk to your doctor about the benefits, risks and possible alternatives to see if it’s the right fit for you.

Frequently Asked Questions

The best time to take Lexapro for anxiety is usually in the morning, as it can help avoid insomnia. However, follow your healthcare provider's instructions for the timing that works best for you.

Lexapro is primarily used to treat anxiety and depression. It helps by balancing chemicals in the brain to improve mood and reduce anxiety symptoms.

No, Lexapro is not a mood stabilizer; it is an antidepressant that primarily treats depression and anxiety. It helps improve mood by increasing serotonin levels in the brain.

Yes, 10 mg of Lexapro is considered a low to moderate dose, often prescribed to start treatment or for mild symptoms. The dose may be adjusted based on individual needs and response.

Yes, weight gain can be a side effect of Lexapro in some individuals, although not everyone experiences it. Lifestyle habits and individual body responses can influence this effect.