What is Papaverine?
Papaverine is a vasodilator, which means it relaxes the smooth muscles in your blood vessels, allowing them to dilate more quickly (widen). This decreases blood pressure and makes it easier for blood to flow into the veins and arteries. An alkaloid found in opium that is structurally and pharmacologically different from the other opium alkaloids. It's a smooth muscle relaxant with a direct action that's used to treat impotence and as a vasodilator, especially for cerebral vasodilation. Its pharmacological actions are unclear, but it appears to be able to inhibit phosphodiesterases and may have direct effects.
Papaverine 60 mg Injections are used to treat erectile dysfunction in men (the failure to sustain an erection long enough for sexual activity). It assists in the expansion of blood vessels and the increase in blood flow.
Papaverine Uses
Papaverine is used to treat a number of disorders that cause smooth muscle spasms. This can include chest pain, circulation issues, a heart attack, or stomach or gallbladder problems. Papaverine should not be administered into the penis and should not be used to treat erectile dysfunction (impotence). This procedure has resulted in painful or prolonged erections, which may lead to surgery. In patients with circulatory disorders, papaverine is used to improve blood flow. It works by relaxing blood vessels, allowing more blood to flow to the heart and across the body.
Papaverine 60 mg injections are prescribed by the doctor, which must not be self-administered. Since long-term use of this drug can lead to dependency, it should only be used for a long time if your doctor recommends it.
Papaverine Side effects
Some of the common side effects of Papaverine are:
- Nausea
- Upset stomach
- Loss of appetite
- Constipation
- Diarrhea
- Headache
- Drowsiness
- Dizziness
- Spinning sensation
- Skin rash
- Increased sweating
- Tiredness and lack of energy
Some of the serious side effects of Papaverine are:
- Dark urine
- Jaundice
- Numbness
- Muscle weakness
- Irregular heartbeat
- Anxiety
- Blurred vision
If you have any of these serious symptoms, see your doctor right away. In any case, if you encounter any side effects from Papaverine, try to prevent it. By seeing the issues, a doctor recommended you to take the drugs, and the benefits of this drug outweigh the side effects.
Precautions
Before taking Papaverine talk with your doctor if you are allergic to it or any other medications. The product may contain some inactive ingredients which can cause some serious allergic reactions or some other problems. Before taking Papaverine talk with your doctor if you are having any medical history such as Heart disease, High blood pressure, Glaucoma and Liver disease. Papaverine should be strictly avoided if a person is having a serious heart condition such as “ AV block.”
How to take Papaverine?
Papaverine is available as a tablet and an extended-release (long-acting) capsule for oral administration. Three to five times a day, at evenly spaced intervals, the tablet is usually taken. Every 8-12 hours, the extended-release capsule is taken. The extended-release capsules should not be crushed, chewed, or split. Follow the directions on your prescription label carefully, and if you have any questions, ask your doctor or pharmacist for clarification. Follow the directions for taking papaverine. It's possible that papaverine is addictive. Do not take higher doses, take it more frequently, or for a longer period than prescribed by your doctor.
Benefits of Papaverine
The blood vessels in your penis relax as you take papaverine. When sexually aroused, this causes blood to rush through the penis and cause an erection. If you are sexually aroused, this drug can just help you get an erection. It is delivered by a doctor or nurse as an injection and should not be self-administered. To get the most value, carefully follow your doctor's instructions.
Missed Dose
Your body will not be harmed if you skip one or two doses of Papaverine. There is no problem with the missed dose. However, if you do not take your medicine on time, it will not work. A sudden chemical change in your body can occur if you miss a dose. If you miss a dose, your doctor can recommend that you take it as soon as possible.
Overdose
In case of an overdose, the patient should consult a doctor immediately. Restlessness, confusion, and dizziness are typical overdose symptoms. The severity of the symptoms can lead to measuring gastric lavage.
Warnings for some serious health conditions
Pregnancy: Using papaverine while pregnant could be dangerous. Animal studies have shown harmful effects on the developing baby, despite the lack of human studies. Before prescribing it to you, your doctor will consider the benefits as well as any potential risks. Please seek medical advice.
Breastfeeding: There is no information on the use of Papaverine 60mg Injection while breastfeeding. Please seek medical advice.
Storage
Direct contact with heat, air and light may damage your medicines. Exposure to medicine may cause some harmful effects. The medicine must be kept in a safe place and out of children’s reach. Mainly the drug should be kept at room temperature between 68ºF and 77ºF (20ºC and 25ºC).
Papaverine vs Drotaverine
| Papaverine | Drotaverine |
|---|---|
| Papaverine is a vasodilator, which means it relaxes the smooth muscles in your blood vessels, allowing them to dilate more quickly (widen). | Drotaverine (INN, also known as drotaverine) is an antispasmodic drug similar to papaverine in structure. Drotaverine is a phosphodiesterase 4 inhibitor that has no anticholinergic properties. |
| Papaverine is used to treat a number of disorders that cause smooth muscle spasms. | Drotaverine is an important treatment for twitches or spasms of the smooth muscles of the stomach and heart. |
Some of the common side effects of Papaverine are:
|
Some of the common and serious side effects of Drotaverine are:
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