Dicycloverine is a commonly used medication that helps relieve stomach and intestinal cramps, especially in conditions like irritable bowel syndrome (IBS). As an antispasmodic agent, it works by relaxing muscles in the digestive tract, easing pain and discomfort.

Available in both tablet and syrup forms, Dicycloverine is a trusted treatment for managing gastrointestinal spasms in people of different age groups.

What is Dicycloverine?

Dicycloverine, also known as dicyclomine hydrochloride, is a medication used to ease abdominal discomfort caused by gastrointestinal muscle spasms.

It falls under the anticholinergic category, meaning it interferes with nerve signals responsible for involuntary muscle movements in the gut, thus reducing pain and cramping.

What Are the Uses of Dicycloverine?

Dicycloverine is primarily used to treat irritable bowel syndrome (IBS), specifically to reduce symptoms of stomach and intestinal cramps. It works by slowing down the natural movements of the gut and relaxing muscles in the stomach and intestines.

Conditions Dicycloverine Treats

Dicycloverine is effective in managing symptoms associated with:

Secondary Uses of Dicycloverine

While primarily used for IBS, Dicycloverine's muscle-relaxing properties may be beneficial in other conditions involving smooth muscle spasms in the gastrointestinal tract, as determined by a healthcare provider.

How Does Dicycloverine Work?

Dicycloverine functions by targeting specific receptors (like M1, M2, and M3) that influence gastrointestinal contractions. It works not only by blocking acetylcholine, a chemical messenger involved in muscle movement, but also by interfering with bradykinin, a compound involved in inflammation and pain signaling. This dual approach helps minimize painful spasms and ease digestive flow.

Dicycloverine Dosage

  • Dicycloverine should be taken orally with or without food as directed by the doctor or pharmacist.
  • To reduce the risk of side effects, the doctor may start you on a lower dose initially.
  • Dicycloverine is available in 10 mg and 20 mg tablets, as well as in liquid form (10mg/5ml).
  • Take dicycloverine as prescribed on the bottle. For adults, the usual dosage is one 10 mg tablet or one 5 ml liquid medicine spoonful three times a day.
  • Follow your doctor's specific instructions if your dosage differs. Swallow the dicycloverine tablet whole with a full glass of water.

Missed Dose

If you forget to take a dose of Dicycloverine:

  • Take it as soon as you remember.
  • If it's nearly time for your next dose, skip the missed dose.
  • Do not double up to make up for a missed dose, as this may increase the risk of side effects.

Overdose Warning

Accidental or intentional overdose of Dicycloverine can be serious. Seek immediate medical attention if you suspect an overdose.

Symptoms of Overdose May Include:

  • Headache
  • Dizziness
  • Nausea
  • Dry mouth
  • Difficulty swallowing
  • Dilated pupils
  • Hot, dry skin
  • Blurred vision

An overdose can lead to life-threatening complications. Avoid exceeding the prescribed dose under any circumstances.

Always use Dicycloverine exactly as prescribed. Consult your doctor if you experience any concerning symptoms.

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Dicycloverine Side Effects:

Dicycloverine can cause a range of side effects, some common and some serious. It's important to consult a doctor if any symptoms worsen.

Common Side Effects

Some of the common Dicycloverine side effects include:

Some of the Serious Side Effects of Dicycloverine are:

Mostly, the doctor will provide medicines based on their benefit and side effects. Many people who are using this medication won't show any serious side effects. Consult with your doctor if you are having any of the above-mentioned serious side effects.

Precautions and Warnings

Before taking Dicycloverine, talk with your doctor if you are allergic to it or any other medications. The product may contain some inactive ingredients that can cause some severe allergic reactions or other problems.

Who Should Avoid This Medicine

Dicycloverine should not be used by individuals with:

  • Hypersensitivity to Dicycloverine or any anticholinergic drugs
  • Closed-angle glaucoma
  • Myasthenia gravis
  • Hemorrhage with cardiovascular instability
  • Paralytic ileus
  • Intestinal atony of elderly/debilitated patients
  • Toxic megacolon
  • GI obstruction
  • Obstructive uropathy
  • Severe ulcerative colitis
  • Reflux esophagitis

Conditions Where Caution is Needed

Before using Dicycloverine, talk with your doctor if you have any serious medical history such as:

  • Enlarged prostate
  • Blocked urinary tract
  • Other stomach problems
  • Overactive thyroid
  • Heart problems
  • High blood pressure
  • Heartburn problems
  • Liver problems
  • Kidney problems

Are There Any Age Restrictions for Using Dicycloverine?

Dicycloverine should not be used in children younger than 6 months old due to a higher risk of experiencing severe side effects, including seizures, respiratory failure, and even death.

Dicycloverine for kids, specifically Dicycloverine 20mg tablets, is generally not recommended for children; consult a paediatrician for appropriate dosing and usage.

Older adults (65 years and older) may also be at greater risk for some side effects, and its use should be discussed with a healthcare provider.

Alcohol or Food Interactions

Avoid alcohol while taking Dicycloverine, as it may increase drowsiness. There are no known interactions between Dicycloverine and foods or drinks. ]However, if you have food poisoning caused by Salmonella bacteria, taking Dicycloverine may cause severe damage to the lower part of your digestive tract.

Possible Interactions with Other Medications (Drug Interactions)

Dicycloverine may interact with other medicines and supplements. Before using Dicycloverine, tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. There are 208 drugs known to interact with dicyclomine.

How Should Dicycloverine Be Stored?

Dicycloverine should be stored in the original container, tightly closed, and kept out of the reach of children.

Recommended Storage Temperature for Dicycloverine

Dicycloverine should be stored at room temperature, between 68ºF and 77ºF (20ºC and 25ºC) . It can be exposed to temperatures between 59ºF and 86ºF (15ºC and 30ºC) for shorter periods, such as during transport. Store it in a cool, dry place, away from direct heat and light.

What Happens If Dicycloverine Is Not Stored Properly?

Direct contact with heat, air, and light may damage your medicines. Exposure of medicine to improper conditions may cause some harmful effects. The medicine must be kept in a safe place and out of children's reach.

Dicycloverine vs Mebeverine

Dicycloverine Mebeverine
Dicycloverine is an antispasmodic drug that is used in the stomach and intestines to alleviate cramps. Mebeverine hydrochloride is classified as an antispasmodic type of medication. It helps with muscle spasms.
Dicycloverine is mainly used for treating a type of intestinal problem called irritable bowel syndrome (IBS). It helps reduce symptoms like stomach and intestinal cramps. Mebeverine is used to ease painful stomach cramps and is also effective in relieving symptoms of irritable bowel syndrome (IBS).
Some of the common side effects of Dicycloverine are:
  • Drowsiness
  • Dizziness
  • Lightheadedness
  • Weakness
  • Blurred vision
  • Dry eyes
Some of the common side effects of Mebeverine are:
  • Skin rash
  • Swelling
  • Dizziness
  • Drowsiness
  • Headache

References

Dicycloverine/Dextropropoxyphene/Paracetamol Overdose | Springer
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Frequently Asked Questions

Dicycloverine syrup is used to relieve symptoms of irritable bowel syndrome (IBS), such as abdominal pain and cramps. It helps relax the muscles in the gastrointestinal tract to ease discomfort.

Yes, Dicycloverine is used to treat symptoms of irritable bowel syndrome, including diarrhea caused by hypermotility. It is considered a first-line treatment in such cases.

Dicycloverine acts by blocking the action of acetylcholine on smooth muscle in the gastrointestinal tract, helping to reduce spasms. Its effects typically begin within 30 to 60 minutes after intake.

Dicycloverine is prescribed to treat the symptoms of irritable bowel syndrome, including stomach cramps and spasms. It is classified as an anticholinergic, which helps relax gastrointestinal muscles.

The typical adult dosage is 10 mg taken three to four times a day, or as prescribed by a healthcare provider.

Dicycloverine syrup works by relaxing the muscles of the stomach and intestines, which helps reduce spasms, pain, and cramping associated with IBS.

Dicycloverine 20mg tablets are generally not recommended for children. Always consult a pediatrician for proper dosage and safety guidelines for children.

Dicyclomine is available under the brand name Bentyl and in generic forms. It comes in several oral dosage forms including 10 mg oral capsules, 20 mg oral tablets, and a 10 mg/5 mL oral liquid (syrup) for easier swallowing. In addition to oral options, dicyclomine is also available as an injectable solution, typically used in clinical settings for faster relief of severe symptoms.

No, dicycloverine is not typically used for acid reflux. It is mainly used to treat stomach cramps, bloating, and irritable bowel syndrome (IBS) by relaxing gut muscles. Acid reflux is better treated with antacids or acid-reducing medications like omeprazole or ranitidine.


Disclaimer: The information provided is accurate and up-to-date to the best of our knowledge. However, it should not be considered a substitute for medical advice or consultation. We do not guarantee its completeness or accuracy. The absence of specific warnings does not mean a medicine is safe for all users. We are not responsible for any outcomes based on this information and strongly recommend consulting a doctor for any medical concerns or questions.

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