What is Cetrorelix?
Cetrorelix is Generic Name of CETROTIDE, a prescription medication used to relieve the effects of infertility. Cetrorelix can be used with or without other medicines.
Cetrorelix belongs from a class of medicines called Gonadotropin Releasing Hormone Antagonists.
Cetrorelix is used in women for some fertility treatments (controlled ovarian stimulation). This medicine works by preventing eggs from being released too early (premature ovulation) by blocking the hormone (gonadotropin-releasing hormone-GnRH) which allows eggs to be released from the ovaries. This gives the eggs time to grow properly. This drug is usually combined with another hormone (human chorionic gonadotropin-hCG) to help you get pregnant.HCG is used to induce the development and release of a mature egg (ovulation). This drug must not be used if you are pregnant. Before your first dose, your doctor can order a pregnancy test.
Cetrorelix is used in women for some fertility treatments (controlled ovarian stimulation). This medicine works by preventing eggs from being released too early allowing eggs to be released from the ovaries. This gives the eggs time to grow properly. This drug is usually combined with another hormone (human chorionic gonadotropin-hCG) to help you get pregnant.
How to use Cetrorelix kit?
- Read the Patient Information Leaflet, if available from your pharmacist, before you start using cetrorelix and any time you refill.clear all queries from your doctor or pharmacist.
- Learn all the guidance for planning and use from your health care provider and the product kit. Follow the instructions to apply the liquid to the drug. Shake the vial gently to blend. Using the liquid directly after mixing.
- Check this product if any discoloration is there or not before use.
- Inject this medicine under the skin as instructed by your doctor, usually a few days a day. It should be injected into the stomach section, at least one inch away from the belly button.
- Carefully follow the doctor's directions on when to start and end the drug.
- Before each dose is injected, clean the injection site with alcohol. Change the injection site each time to reduce the damage to the skin.
- Use this drug exactly as instructed by your doctor to make the most of it. Do not raise your dosage or use this medication more frequently or longer than necessary.
- Learn proper storage and disposal processes of medical supplies.
Cetrorelix Side Effects
Some of the common side effects of Cetrorelix are:
- Pain / Bruising / Redness / Swelling / Swelling at the injection site can occur.
Many people who use this drug do not have significant side effects.
This medicine can cause a condition known as ovarian hyperstimulation syndrome (OHSS). These issues can occur during or after treatment. Seldom, intense OHSS causes fluid to build up suddenly in the stomach, chest, and heart.
Get medical attention right away if you experience the following side effects:
- Extreme pain
- Swelling in the lower abdominal (pelvic) region
- Sudden / fast weight gain
- Decreased urination
- Difficulty in breathing
Before using cetrorelix, inform your doctor or pharmacist whether you are allergic to it or to other gonadotropin-releasing hormone (GnRH) products; or if you have any other allergies. This product can contain inactive ingredients that may cause allergic reactions or other problems. Please talk to your health care advisor for more information.
Before taking this drug, tell your doctor or pharmacist your medical history, especially the following: history of serious allergic reactions, kidney disease.
Tell your doctor of all the things you need when you have surgery (such as prescription drugs, nonprescription drugs, and herbal products).
Avoid taking this drug if you are pregnant. This drug must not be taken while you are pregnant. If you think you are pregnant, ask your doctor about risk and benefits.
It is not clear whether this medication is transferred into breast milk. Owing to the potential risk to the child, breast-feeding is not recommended during use of this drug. Please consult your doctor.
Drug interactions can cause reactions and change the way your drugs work or increase your risk of serious side effects. Keep a check on all the medications you use including prescribed and non prescribed drugs and any herbal products) and share them with your doctor and pharmacist. Do not start, stop or change the dosage of any drug without your doctor's permission.
When someone has overdosed and has extreme signs such as passing out or respiratory problems
- Do not share with anyone this drug.Do not share with anyone this drug.
- Laboratory and/or diagnostic tests (such as cervical ultrasound, hormone levels) can be performed when you are using this drug. Keep all medical and laboratory appointments in place. For more info, contact your doctor.
It is very important to follow the schedule. In case you miss any dose consult an expert.
Different products have different storage requirements. Please refer to the storage details printed on your package for the exact temperature range
Do not flush the medication in toilets, washrooms or drains.
For Adult: Dosage Forms & Strengths
Single-dose regimen should be 3 mg SC, serum estradiol levels show appropriate stimulation response which is day 7; if hCG not administered within 4 days, continue dose at 0.25 mg/day until hCG administered
- 0.25 mg SC two times a day, morning or evening of stimulation day 5 or morning of stimulation day 6; continue until hCG administered
- For Pediatric use, it is not recommended
Mechanism for action
Cetrorelix binds to the hormone receptor-releasing gonadotropin and functions as a potent inhibitor of gonadotropin secretion. It competes with natural GnRH for binding to pituitary cell membrane receptors and thus regulates the release of LH and FSH in a dose-dependent manner.
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