What is Acebutolol?

Acebutolol is a beta-blocker for the treatment of hypertension and arrhythmias, marketed under the brand name Sectral, among others. Acebutolol is a prescription medicine. It's delivered as an oral capsule. As the brand-name drug Sectral, and as a generic drug, Acebutolol oral capsule is available. In some cases, they might be not available as a brand-name drug in all strengths or forms. As part of combination therapy with other drugs, acebutolol can be taken.

Acebutolol Uses

  • Acebutolol is used for treating high blood pressure and pulse irregularities (arrhythmia). Lowering the high blood pressure helps you to avoid health conditions such as strokes, kidney complications, and heart attacks. The heart functions better and with less pressure by treating irregular heartbeats. Irregular heartbeats may be extreme and can even lead to a heart attack occasionally
  • This medication belongs to a class of drugs referred to as beta-blockers. It works by blocking the heart and blood vessels from operating on the natural substances in your body, such as epinephrine. This effect decreases heart rate, blood pressure, and heart strain.
  • Forms and strengths
    Generic - Acebutolol
  • Form- oral capsule
    Strengths- 200 mg, 400 mg
    Brand- Sectral
  • Form- oral capsule
    Strengths- 200 mg, 400 mg

How to use

  • Take this medication by mouth, as directed by your doctor, with or without food, usually once or twice a day. The dosage is based on your medical condition and your treatment response.
  • To get the most benefit from it, use this medication periodically. To help you recall, take it each day at the same time(s).
  • It may take several weeks before you get the full benefit of this drug for the treatment of high blood pressure. Even if you feel well, keep on taking this medication. The majority of individuals with high blood pressure do not feel sick.
  • If your condition does not get improved, or if it starts getting worse, tell your doctor (for example if your routine blood pressure readings remain high or increase).

How does it work

  • Acebutolol belongs to a drug class known as beta-blockers. A group of medicines that function in the same way is a class of drugs. For the treatment of related conditions/health issues, these medications can also be used.
  • This medication works by blocking hormones, such as adrenaline, from activating certain receptors (beta) located in your blood vessels and heart. Your blood vessels and heart remain relaxed by preventing the activation of these receptors. This helps decrease your pulse and blood pressure.
  • High blood pressure also occurs when you tighten your blood vessels. That strains the heart and boosts the need for oxygen in your body. Acebutolol also helps reduce your heart rate and the demand for oxygen from your heart.

Side Effects

Some of the common side effects of Acarbose are:

  • There may be fatigue, dizziness, lightheadedness, nausea, upset stomach, slow heartbeat, or sleeping difficulties. Tell your physician or pharmacist promptly if any of these effects persist or worsen.
  • Get up slowly when waking up from a sitting or lying position to decrease the risk of dizziness and lightheadedness.
  • This medication may decrease the flow of blood to your hands and feet, making them feel cold. This effect may worsen smoking. Dress warmly and avoid any use of tobacco.
  • Remember that this medication has been prescribed to you by your doctor because he or she has decided that your benefits of health are much greater than the risk of side effects.
  • Tell your doctor immediately if you experience any serious side effects, including symptoms of asthma (such as chest tightness, shortness of breath, cough, wheezing), blue fingers/toes, fainting, very slow heartbeat, new or worsening symptoms of heart failure (such as shortness of breath, swelling of the ankles/feet, unusual tiredness, unusual/sudden gain of weight), mental/mood changes (s/mood changes).
  • It is rare to experience a very serious allergic reaction to this drug. However, if you notice any symptoms of a serious allergic reaction, including rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing, get medical assistance immediately.
  • This is not a complete list of side effects that might be possible. Contact your doctor if you notice other effects that are not listed above.


  • Tell your doctor or pharmacist whether you are allergic to it or whether you have any other reactions before using acebutolol. There may be inactive ingredients in this substance that may cause allergic reactions or other problems. For more knowledge in depth, talk to your pharmacist.
  • Tell your doctor or pharmacist your medical history before using this medication, especially: problems with blood circulation (such as Raynaud's disease, peripheral vascular disease), breathing problems (such as asthma, chronic bronchitis, emphysema), heart problems (such as heart failure, previous heart attack, problems with heart rhythms), kidney problems, problems with the liver, mental/mood disorders (such as depression), Myasthenia gravis, overactive thyroid disorder (hyperthyroidism), extreme allergic reactions, including those requiring epinephrine treatment.
  • You can get dizzy with this medication. Alcohol or cannabis (cannabis) will make you dizzier. Do not do the driving, use big tools, or do something that involves safety before you can do it safely. To ban alcoholic drinks. If you are habituated to take marijuana, talk to your doctor (cannabis).
  • This product can mask the fast/pounding heartbeat you would normally feel when your blood sugar falls too low if you have diabetes (hypoglycemia). This medication is unaffected by other signs of low blood sugar, such as dizziness and sweating. Your blood sugar may also be more difficult to regulate with this product. As instructed, regularly check your blood sugar levels and share the results with your doctor. If you have signs of elevated (or change) blood sugar, such as increased thirst/urination, inform your doctor immediately. Your doctor may require to change the drug dosage, exercise regimen, or diet schedule for your diabetes.
  • This drug should be used during pregnancy only when it is obviously needed. During pregnancy, babies born to mothers taking this drug may have a low birth weight and need monitoring for issues such as low blood pressure and sluggish heartbeat.
  • This medication is added to breast milk. Before breastfeeding, consult the doctor.


Drug interactions might affect/change the working of your drugs or increase the risk of some serious side effects. Without your doctor's permission, do not start taking medicine, stop taking, or adjusting on your own the dosage of any medication. Fingolimod is a product that can interfere with this drug. There are many additives in certain drugs that could boost the heart rate or blood pressure. Tell your pharmacist about what products you have been using since last time and ask your pharmacist how to use them safely (especially cough and cold products, diet aids, or NSAIDs).

Acebutolol contraindications

There is a particular group that’s not supposed to take Acebutolol HCL. With this drug, the conditions below are contraindicated. Check with your doctor if you have any of the following groups:

  • pheochromocytoma
  • diabetes
  • depression
  • myasthenia gravis
  • a skeletal muscle disorder
  • complete heart block
  • second-degree atrioventricular heart block
  • sinus bradycardia


The efficacy of this drug can be improved by lifestyle improvements such as stress reduction services, exercise, and dietary changes. Speak to your doctor or pharmacist about improvements in your lifestyle that could help you.

When taking this drug, monitor your blood pressure and pulse (heart rate) regularly. Learn how to monitor and share the results with your doctor about your blood pressure and pulse at home.


When swallowed, this drug can be harmful. Call or directly go to a poison control center immediately if someone has overdosed and has severe signs such as passing out or difficulty in breathing.

Missed Dose

If a dose is missing, use it as soon as you know. If it is almost the time for the next dose to be taken is close, skip the forgotten dose. At a normal time, use the next dose. do not double the dosage.


Store it away from light and moisture at room temperature between 59-86 degrees F (15-30 degrees C). You don't freeze. Do not store your medications in the washroom. Do not flush drugs down the toilet or dump them into a drain unless told to do so. Discard this drug correctly when it expires

Acebutolol vs Metoprolol



Formula: C18H28N2O4 Formula: C15H25NO3
Sold under brand Sectral Metoprolol, sold under the brand name Lopressor
Used for treating high blood pressure and irregular heartbeat used for treating high blood pressure, chest pain due to poor blood flow to the heart
Oral form available Oral form available

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Frequently Asked Questions

What are the side effects of Acebutolol?

Fatigue, dizziness, lightheadedness, nausea, upset stomach, slow heartbeat, or sleeping difficulties are some common side effects.

Does Acebutolol cause weight gain?

Alpha-blockers, including prazosin and clonidine, show little weight gain if any. And acebutolol and timolol are neutral in weight. In addition, some weight gain can be predicted when transitioning from a diuretic to a beta-blocker.

What class of drug is Acebutolol?

Acebutolol is used to treat hypertension. Acebutolol is also used to treat heartbeats that are irregular. Acebutolol belongs to a family of drugs called beta-blockers. It acts to increase blood flow and to decrease blood pressure by calming blood vessels and slowing the heart rate.

Is Acebutolol selective?

Acebutolol is known to be a "selective" beta-adrenergic receptor blocker since it has potent activity against adrenergic beta-1 receptors found in cardiac muscle, but has little or no activity against adrenergic beta-2 receptors found in smooth bronchial and vascular muscle.

What is Acebutolol?

Acebutolol is a beta-blocker for the treatment of hypertension and arrhythmias, marketed under the brand name Sectral, among others. Acebutolol is a prescription medicine. It's delivered as an oral capsule. As the brand-name drug Sectral, and as a generic drug, Acebutolol oral capsule is available.

Is Acebutolol a partial agonist?

Acebutolol is a modern beta-adrenergic-blocking hydrophilic, cardioselective agent that has partial agonist and membrane-stabilizing activities.

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