Angelman Syndrome

What is Ashermans Syndrome?

Asherman's Syndrome, also known as intrauterine adhesions or uterine synechiae, is a condition involves the formation of scar tissue (adhesions) within the uterine cavity. These adhesions can cause a range of menstrual and reproductive problems.

Types:

Asherman's Syndrome, also known as intrauterine adhesions,separated into different types based on the seriousness and extent of the adhesions within the uterine cavity.Here are the commonly recognized types of Asherman's Syndrome:

  • Mild (Grade 1): In this type, there are thin and filmy adhesions that involve only a small portion of the uterine cavity. These adhesions may not cause significant symptoms and might not affect fertility as much. Treatment might involve hysteroscopic adhesion removal and hormonal therapy.
  • Moderate (Grade 2): Moderate adhesions are thicker and involve a larger area of the uterine cavity. These adhesions can lead to more pronounced menstrual irregularities and could impact fertility to a greater extent. Hysteroscopic adhesion removal might still be effective, but more extensive procedures could be required.
  • Severe (Grade 3): Severe adhesions are dense and involve a substantial portion of the uterine cavity. These adhesions can cause significant menstrual disruptions, infertility, and other reproductive issues. Treatment might involve more complex surgical techniques, such as placing intrauterine devices or performing multiple surgeries.
  • Total (Grade 4): Total adhesions involve the near-complete or complete obliteration of the uterine cavity. This is the most severe form of Asherman's Syndrome and can lead to amenorrhea (absence of menstruation) and a high risk of infertility. Treatment can be challenging and may involve multiple surgical interventions.

Symptoms:

The symptoms of Asherman's Syndrome can include:

Menstrual Irregularities

Infertility

Pain

Recurrent Pregnancy Loss

Abnormal Bleeding

When to see a Doctor:

If you suspect you might have Asherman's Syndrome or are experiencing the mentioned symptoms, seeking consultation with the appropriate healthcare professional can lead to accurate diagnosis and suitable treatment. It is advisable to consult specialized doctors, including gynecologists, reproductive endocrinologists, obstetricians, fertility specialists, and gynecological surgeons, who can provide optimal care at the Best Women's healthcare hospital.


Causes:

The primary cause of Asherman's Syndrome is uterine trauma, often resulting from procedures that involve scraping or trauma to the uterine lining. Common causes include:

Dilation and Curettage (D&C): This is a procedure often performed after miscarriage, abortion, or to remove tissue from the uterus. If not performed carefully, it leads to damage of the uterine lining.

Childbirth Complications: Trauma during childbirth, especially if there is excessive bleeding or retained placental tissue, can increase the risk of scar tissue formation.

Uterine Surgery: Surgeries such as myomectomy (removal of uterine fibroids) or removal of polyps can also result in uterine adhesions if not done meticulously.

Uterine Infections: Infections that affect the uterine lining, such as endometritis, can trigger the growth of scar tissue as part of the healing process.


Treatment:

The treatment of Asherman's Syndrome aims to remove intrauterine adhesions and restore the normal functioning of the uterine cavity. The specific method of therapy depends on the severity of the adhesions, the symptoms experienced, and the patient's reproductive goals. Here are the main treatment options:

Hysteroscopic Adhesion Removal: Hysteroscopy is the primary method for diagnosing and treating Asherman's Syndrome. To visualize the uterine cavity, a hysteroscope, a thin tube with a camera, is inserted via the cervix. Adhesions are then removed using specialized instruments. This minimally invasive procedure allows for precise adhesion removal while preserving the uterine lining.

Adhesion Prevention: After adhesion removal, measures might be taken to prevent their recurrence. This can include placing barriers, such as intrauterine devices (IUDs) or special balloon devices, to prevent adhesions from re-forming as the uterine lining heals.

Hormonal Therapy: Following adhesion removal, hormonal therapy, often involving estrogen, may be prescribed. Estrogen helps stimulate the regrowth of the uterine lining (endometrium) and prevents new adhesions from forming. Progestin might also be added to support endometrial development.

Surgery: In severe cases, especially when adhesions are extensive or if the initial hysteroscopic treatment is unsuccessful, more extensive surgical procedures might be required. These could involve more complex surgeries to restore the uterine cavity's shape and function.

Reproductive Assistance: If infertility is a concern, assisted reproductive technologies (ART), such as in vitro fertilization (IVF), may be recommended. IVF bypasses the uterine cavity, allowing for successful pregnancy despite the presence of scar tissue.

Postoperative Care: After any treatment, it's important to follow your doctor's instructions for postoperative care. This may include resting, avoiding strenuous activities, taking prescribed medications, and attending follow-up appointments to monitor your progress.

Emotional Support: Coping with the diagnosis and treatment of Asherman's Syndrome can be emotionally challenging. Taking support from mental health professionals, support groups, or counseling services can be beneficial.


Risk Factors for Asherman's Syndrome:

Few factors can raise the risk of developing Asherman's Syndrome:

Uterine Procedures: Women who have undergone uterine surgeries, such as dilation and curettage (D&C), myomectomy, or removal of polyps, are at a higher risk due to the potential for trauma to the uterine lining.

Multiple D&C Procedures: Repeated D&C procedures, especially within a short time frame, increase the risk of scar tissue formation.

Childbirth Complications: Women who experienced complications during childbirth, such as retained placental tissue or excessive bleeding, are at a higher risk of developing adhesions.

Infections: Uterine infections, particularly those that cause inflammation of the endometrium (endometritis), can lead to the growth of scar tissue throughout the healing process.

Advanced Maternal Age: Women who become pregnant at an alter age may have a higher risk of developing complications during pregnancy or childbirth that could contribute to Asherman's Syndrome.

Lack of Proper Management: Poor surgical technique during uterine procedures, inadequate postoperative care, or failure to diagnose and treat infections can increase the risk of adhesion formation.


Complications of Asherman's Syndrome:

Infertility: One of the most significant complications of Asherman's Syndrome is infertility. Adhesions within the uterine cavity can prevent the implantation of a fertilized egg or interfere with the normal development of the placenta during pregnancy.

Menstrual Irregularities: Adhesions can disrupt the normal shedding of the uterine lining during menstruation, leading to irregular, lighter, or absent periods.

Amenorrhea: Severe adhesions can lead to the complete absence of menstruation, a condition known as amenorrhea.

Pregnancy Complications: If pregnancy occurs despite the presence of adhesions, it can be associated with a higher risk of miscarriage, preterm birth, and abnormal placental attachment (placenta accreta, increta, or percreta).

Pain: Scar tissue can cause pelvic pain, especially during menstruation, as it can obstruct the normal contractions of the uterus.

Recurrent Pregnancy Loss: The compromised uterine environment caused by adhesions can increase the risk of recurrent miscarriages.

Adhesion Recurrence: Even after successful treatment, there is a risk of adhesions reoccurring, particularly if proper postoperative care is not maintained.

Emotional Impact: The inability to conceive or carry a pregnancy to term can lead to emotional distress, anxiety, and depression.


Diagnosis:

Diagnosing Asherman's Syndrome involves a combination of medical history, physical examination, and imaging techniques.Here are the key steps involved in diagnosing Asherman's Syndrome:

Medical History

Physical Examination

Imaging Techniques:

Hysteroscopy

Transvaginal Ultrasound

Sonohysterography or Hysterosalpingography

MRI (Magnetic Resonance Imaging)

Symptoms and History


Dos and Don’ts Asherman's Syndrome

Do's Don'ts
Do Seek Medical Guidance Don't Delay Treatment
Do Share Your Medical History Don't Self-Diagnose or Self-Treat
Do Follow Postoperative Care. Don't Ignore Symptoms
Do Maintain Good Hygiene Don't Skip Follow-Up
Do Communicate Don't Engage in Strenuous Activities
Do Adopt a Healthy Lifestyle Don't Ignore Emotional Well-being
Do Educate Yourself Don't Delay Fertility Planning
Do Stay Informed Don't Use Invasive Procedures without Medical Advice

Asherman's Syndrome Care at Medicover:

At Medicover, we offer comprehensive and specialized care for Asherman's Syndrome, a condition characterized by intrauterine adhesions that can impact fertility and reproductive health. Our dedicated team of experienced gynecologists, reproductive endocrinologists, and surgical experts is committed to providing personalized treatment options to help you achieve the best possible outcomes.