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Toradol

toradol

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By Medicover Hospitals / 11 Mar 2021
Home | Medicine | Toradol

What is Toradol ?

  • Toradol (ketorolac) is a nonsteroidal anti-inflammatory medication (NSAID). It works by lowering hormones in the body that cause inflammation and pain. Toradol is used to treat moderate to severe pain for a short period of time (5 days or less).
    1. Toradol Uses
    2. Toradol Side effects
    3. Precautions
    4. Overdose
    5. Storage
    6. Toradol vs Meloxicam
    7. Frequently Asked Questions
    8. Citations

    Toradol Uses:

  • In adults, it is used to treat moderate to severe pain in the short term. It is typically used prior to or following medical procedures or surgery. Reducing pain allows you to recover more comfortably and return to your normal daily activities. This is a nonsteroidal anti-inflammatory medication (NSAID). It works by inhibiting the production of inflammation-causing natural substances in your body. This effect aids in the reduction of swelling, pain, and fever. It should not be used to treat minor or chronic pain (such as arthritis).
  • How to use?

    • Before you start taking this, carefully read the medication guide and the patient information leaflet provided by your pharmacist.
    • Take this medication orally with a full glass of water for every 4 to 6 hours, or as guided by your doctor. After taking this medication, don’t lie down for 10 minutes. To avoid stomach upset while taking this medication, take it with food, milk, or an antacid.
    • The dose is evaluated by your medical condition and response to treatment. Take this medication at the lowest possible dose for the shortest possible time to decrease your risk of stomach bleeding and other side effects. Do not increase the dose for more than 5 days. If you are still in pain after 5 days, consult your doctor about other medications you could try. Do not exceed 40 milligrams in a 24-hour period.
    • If you are taking this medication "as needed" (not on a routine basis), keep in mind that pain medications work best when taken as soon as the first signs of pain appear. If you wait until the pain has become unbearable, the medication may not work as well.

    Toradol Side Effects:

  • More common side effects are
    • Swelling
    • weight gain (unusual)
    • Upset stomach
    • Nausea
    • Vomiting
    • Constipation
    • Diarrhea
    • Gas
    • Dizziness
    • Drowsiness
  • Less common side effects are
    • Bruising
    • High blood pressure
    • Skin rash
    • Itching
    • Red spots on the skin
    • Sores
    • Ulcers
    • White spots on lips or in mouth

    Precautions:

    • Before taking it, tell your doctor if you are allergic to aspirin, or other NSAIDs (such as ibuprofen, naproxen, or celecoxib), or if you have any other allergies.
    • Tell your doctor about your medical history, especially if you have: asthma, bleeding or clotting problems, blood disorders, heart disease, high blood pressure, liver disease, nasal polyps, throat or intestinal problems, stroke, or swelling of the ankles.
    • Kidney problems have been linked to the use of NSAIDs, including this medicine. Stay hydrated as directed by your doctor to avoid dehydration, and notify your doctor immediately if the amount of urine changes.
    • This medication may cause dizziness or drowsiness. Alcohol can cause dizziness or drowsiness.
    • This medication has the potential to cause stomach/intestinal bleeding to people who take alcohol on a regular basis, especially when taking this medication. Limit your alcohol consumption.
    • Senior citizens might be more prone to the drug's side effects, particularly stomach/intestinal bleeding, kidney problems, heart attack, and stroke. Long-term use of high doses may increase this risk.
    • Inform your doctor if you are pregnant before taking this medication. This medication has the potential to harm an unborn baby and cause complications during normal labor. It is not advised to be used during pregnancy from 20 weeks until delivery. If your doctor determines that you must take this medication between 20 and 30 weeks of pregnancy, you should take the lowest effective dose for the shortest amount of time. This medication should not be used after 30 weeks of pregnancy.
    • This medication enters the breast milk. Before breastfeeding consult your doctor.

    Interactions:

    • Drug interactions can change the way your medications function or put you at risk for serious side effects.
    • Aliskiren, ACE inhibitors (such as captopril and lisinopril), angiotensin II receptor blockers, lithium, methotrexate, probenecid, corticosteroids, and other kidney-related medications may interact with this medication.
    • When used with other drugs that might cause bleeding, this medication may increase the risk of bleeding. Antiplatelet drugs such as clopidogrel and blood thinners such as dabigatran/enoxaparin/warfarin are examples.

    Overdose:

  • If you have taken an overdose of this medicine and have serious symptoms such as trouble breathing, seek medical advice. Never take more than what is prescribed to you by your doctor.
  • Missed Dose:

  • If you forget to take any dosage or by mistake miss a dose, take it as soon as you remember it. If it is already the time for the next dose, skip the forgotten dose. Take your next medicine at the regular time schedule. Do not double the dose.
  • Storage:

  • The medicine should not come in direct contact with heat, air, light and may damage your medicines. Exposure to medicine might cause some harmful effects or serious side effects. The medicine must be kept in a safe place and out of children’s reach.
  • Toradol vs Meloxicam:

    Toradol
    Meloxicam
    Toradol is a nonsteroidal anti-inflammatory drug that is used for treating pain. The recommended treatment period is less than six days. Meloxicam, also known as Mobic, is a nonsteroidal anti-inflammatory medication used to treat pain and inflammation in rheumatic diseases and osteoarthritis.
    It is used to treat moderately severe pain and inflammation following surgery. It is a medication used to treat arthritis. It alleviates swelling, joint pain, and stiffness
    Toradol works by inhibiting the production of prostaglandins, which are responsible for pain, fever, and inflammation. Works by inhibiting the action of natural chemicals known as cyclo-oxygenase (COX) enzymes. These enzymes aid in the production of other chemicals in the body known as prostaglandins.

    Frequently Asked Questions:

    Toradol is a nonsteroidal anti-inflammatory medication (NSAID). It does not contain any narcotics. Toradol is not addictive, but it is a potent NSAID with serious side effects. You should also avoid taking it for extended periods of time.
    Toradol causes drowsiness in some patients. This happens in 1% to 10% of patients. Toradol's most common side effects are stomach pain, indigestion, nausea, and headache.
    Advil (ibuprofen) is a pain reliever and anti-inflammatory medication. It relieves moderate to severe short-term pain. It is a relatively strong NSAID. However, because it increases your risk of bleeding, it should only be used for as short a period of time as possible.
    For decades, parenteral ketorolac tromethamine (Toradol) has been used successfully to treat postoperative pain. However, due to an increased risk of gastrointestinal (GI) bleeding, its use is limited to 5-day treatment duration. The solution is given as a single Toradol 15 mg - 60mg dose every 6 hours, with a maximum daily dose of 60 or 120 mg.
    The common side effects of this include gain in weight. So it may or may not cause weight gain in some patients
    This is a nonsteroidal anti-inflammatory medication (NSAID). It works by inhibiting the production of certain natural substances in your body that cause inflammation. This effect aids in the reduction of swelling, pain, and fever.
    Toradol is a non-opioid pain reliever that is used to treat moderate to severe pain. It is used to manage pain before or after medical procedures such as surgery, allowing you to return to your daily activities as soon as possible.
    Toradol tablets have an average elimination half-life of 5 to 6 hours. This is the amount of time it takes your body to reduce plasma levels by half. It takes approximately 5.5 times the elimination half-life for a drug to be completely eliminated from your system. As a result, it would be present in your system for approximately 33 hours (6 x 5.5 hours).
    Toradol injections are administered every 4 to 6 hours as needed, with a maximum daily dose of 90 mg.
    Toradol should be used with caution in patients who have impaired liver function or a history of liver disease. Up to 15% of patients taking NSAIDs, including Toradol, may experience borderline elevations in one or more liver tests

    Citations:

  • Toradol , https://www.sciencedirect.com/science/article/abs/pii/S0022534717362614
  • Toradol effects, https://europepmc.org/article/med/8863973