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Rifampin

rifampin
By Medicover Hospitals / 15 Jan 2021
Home | Medicine | Rifampin

Rifampin is an antibiotic which is used for the treatment of tuberculosis. It can also be used for reducing certain bacteria in nose and throat which would cause meningitis or any other infections. Rifampin tablets also prevent you from spreading these bacteria to other people, but it will not treat an active meningitis infection. It is also used to treat infections present in nose and throat.

  1. Rifampin Uses
  2. Rifampin side effects
  3. Precautions
  4. Rifampin Dosage
  5. Rifampin Warnings
  6. Rifampin Storage
  7. Rifampin vs Metronidazole
  8. Frequently Asked Questions
  9. Citations

Rifampin Uses

  • Rifampin is used for treating tuberculosis and other infections.
  • The Rifampin tablets treat only bacterial infections.
  • Rifampin is used for treating Neisseria meningitides, infection cause in their nose and throat.

Rifampin Side Effects:

Some common side effects of Rifampin:

  • Discoloration in skin
  • Itching
  • Headache
  • Drowsiness
  • Dizziness
  • Behavioral change
  • Muscle weakness
  • Pain in full body
  • Heartburn
  • Stomach cramps
  • Loss of appetite
  • Nausea
  • Vomiting
  • Diarrhea
  • Gas
  • Irregular menstrual periods

Some of the major side effects of Rifampin tablets are:

  • Breathlessness
  • Cough and Chest Pain
  • Nose bleeding and bleeding gums
  • Irregular heartbeat
  • Liver problems (Dark urine, jaundice)

If you have any of these serious symptoms immediately contact your doctor for further assistance. In any case, due to Rifampin if you get any kind of reactions in your body try avoiding it.

A doctor advised you to take the medicines by seeing your problems and the benefits of this medicine are greater than the side effects. Majority of the people who use this medicine don’t show any side effects. Get medical help immediately if you get any serious Rifampin side effects.

Precautions:

Before taking this Rifampin tell your doctor if you are allergic to any the medications, vitamins, nutritional supplements and other herbal products if you are taking or planning to take. There are many drugs that can interact and cause some dangerous effects. Some of the drugs should not be taken with rifampin.

Before taking this medicine tell your doctor if you are having allergies. This tablet can contain some inactive ingredients which can lead to allergic reactions or any other problems. If you are taking Rifampin avoid the consumption of alcohol as it has a direct impact on the liver.

Talk to your doctor if you ever had these diseases:

  • Diabetes
  • Liver Disease
  • Bleeding problems
  • Porphyria- It’s a genetic enzyme disorder which will have a direct impact on skin and nervous systems.

How to get rid of the side effects?

Nausea- Avoid eating spicy foods while taking rifampin. Try to have simple meals.

Losing of appetite- Eat small meals for every 2-3 hour break. Try having nutritious snacks which are high in calories and protein

Headaches- Drink plenty of water. If you are facing a severe headacheask your doctor to prescribe you with pain killers.

How to take Rifampin?

Rifampin comes in Capsule forms and this medication should be taken in empty stomach with a full glass of water 1 hour or 2 hours before the meal. If Rifampin tablets are used for treating tuberculosis then it should be taken once daily.

If rifampin tablets are used for treating Neisseria meningitides then it can be taken twice daily for 2 days or once daily for 4 days. Tell your doctor if you are not able to swallow the tablets your doctor can ask you to take liquids.

Dosage:

Name of the drug:
Rifampin

Brand Names:
Rifadin, Rimactane

Capsules-150mg, 300mg

Liquid medicine- 100mg per 5ml

Children-
The bacteria which cause tuberculosis are very hard to kill. Therefore the dosage should be taken for 3-6 months. The dose should depend on the weight of the children.

Missed Dose:

Missing one or two-dose of Rifampin won’t show any effect on your body. The skipped dose causes no problem. But with some medication, it won’t work if you don’t take the dosage on time. If you miss a dose some sudden chemical change may affect your body. In some cases, your doctor would advise you to take the prescribed medicine as soon as possible if you have missed the dose.

Overdose:

Overdose of a drug can be accidental. If you have taken more than the prescribed Rifampin tablets there is a chance of getting a harmful effect on your body’s functions. Overdose of a medicine can lead to some medical emergency.

Rifampin Warnings:

  • Allergic reaction
  • Trouble breathing
  • Hives
  • Swelling of throat or tongue
  • Some severe skin reactions

Warnings for some serious health conditions:

Pregnant women
Rifampin is not evaluated for pregnant women. If a woman is using the drug during her pregnancy there is no such high risk of pregnancy loss, birth defects or any other problems. But to be on safe side consult your doctor before taking the medicine. If this medication is used in the last weeks of pregnancy then it may cause bleeding in mother or can affect the newborn baby.

Breastfeeding
Rifampin passes into breast milk. It can cause some side effects to a child who is breastfed. These can include diarrhea, vomiting and rash. Before taking Rifampin while breastfeeding consult your doctor.

Storage:

Direct contact with heat, air and light may damage your medicines. The exposure of medicine may cause some harmful effects. The medicine must be kept in a safe place and out of children’s reach.

Mainly the drug should be kept at room temperature between 68ºF and 77ºF (20ºC and 25ºC).

Before taking Rifampin consult your Doctor. In case if you face any problems or get any side effects after taking Rifampin rush immediately to your nearby hospital or consult your doctor for better treatment. Carry your medications always in your bag while travelling to avoid any immediate emergencies. Follow your prescription and follow your Doctor advice whenever you take Rifampin.

Rifampin vs Metronidazole:

Rifampin Metronidazole
Rifampin is an antibiotic which is used for the treatment of tuberculosis. It can also be used for reducing certain bacteria in nose and throat which would cause meningitis or any other infections. Metronidazole is an antibiotic that helps in fighting with bacteria. This is used for treating many bacterial infections that are caused in vagina, stomach, intestines, liver, skin, joints, brain, heart and respiratory tract.
Some common side effects of Rifampin:
  • Discoloration in skin
  • Itching
  • Headache
  • Drowsiness
  • Dizziness
  • Behavioral change
  • Muscle weakness
  • Pain in full body
Some common side effects of metronidazole are:
  • Vomiting
  • Nausea
  • Diarrhea
  • Constipation
  • Stomach problem
  • Stomach cramps
  • Loss of appetite
Rifampin Uses:
  • Rifampin is used for treating tuberculosis and other infections.
  • The Rifampin tablets treat only bacterial infections.
Metronidazole antibiotics are used for treating many bacterial and parasitic infections. These tablets are not used for viral infections such as cold and flu

Frequently Asked Questions:

Rifampin is an antibiotic which is used for the treatment of tuberculosis. It can also be used for reducing certain bacteria in nose and throat which would cause meningitis or any other infections.
Some common side effects of Rifampin:
  • Discoloration in skin
  • Itching
  • Headache
  • Drowsiness
  • Dizziness
Yes, Rifampin is a strong antibiotic which helps in treating tuberculosis. This medicine treats only infections created by bacteria.
Rifampin tablets are used to kill all type of bacterial infections. It is used for treating tuberculosis disease.

Citations:

  • Rifampin, https://www.karger.com/Article/PDF/220462
  • Rifampin Dosage, https://link.springer.com/article/10.2165/00003088-200342090-00003