Fahimtar Medullary Thyroid Cancer
Medullary thyroid ciwon daji (MTC) wani nau'in ciwon daji ne da ba kasafai ba, yana lissafin kusan kashi 1-2% na duk cututtukan daji na thyroid. Duk da ƙarancinsa, fahimtar MTC yana da mahimmanci saboda halayensa na musamman da abubuwan da ke tattare da kwayoyin halitta.
Menene Medullary Thyroid Cancer?
Medullary thyroid ciwon daji ya samo asali daga parafollicular C-cells na thyroid, wanda ke da alhakin samar da hormone calcitonin. Ba kamar sauran cututtukan cututtukan thyroid waɗanda ke fitowa daga ƙwayoyin follicular ba, asalin asalin MTC yana shafar halayensa da amsawar jiyya.
Tabbatar da lafiyar ku tare da ra'ayi na biyu. Yi shawarwarin da aka sani kuma ku yi alƙawarinku a yau!
Samun Ra'ayi Na BiyuDalilai da Juyin Halitta
Ci gaban ciwon daji na medullary thyroid sau da yawa yana da alaƙa da maye gurbi. Kusan kashi 25% na lokuta na iyali ne, masu alaƙa da Multiple Endocrine Neoplasia type 2 (MEN2) ciwo. Wadannan maye gurbi na kwayoyin halitta, musamman a cikin proto-oncogene na RET, suna taka muhimmiyar rawa a cikin pathogenesis na MTC. Wannan yana nuna mahimmancin gwajin kwayoyin halitta ga mutanen da ke cikin haɗari, yana ba da damar ganowa da gudanarwa da wuri.
Gane Medullary Thyroid Cancer Alamomin
Gano alamun cutar kansar thyroid na medullary da wuri yana da mahimmanci don ganowa da jiyya akan lokaci. Alamomin gama gari sun haɗa da:
- Yawan wuyan wuya ko kullutu
- Girma ko murya ta canza
- Difficile haɗiye
- Ara girman ƙwayoyin lymph
- m tari rashin alaka da mura
Saboda yanayin samar da calcitonin na MTC, haɓakar matakan calcitonin na jini na iya zama alamar halitta, sau da yawa yana nuna kasancewar cutar tun kafin bayyanar cututtuka ta jiki.
Ganewar Ciwon Ciwon Ciwon Jiki na Medullary
Gano MTC ya ƙunshi haɗakar gwajin jiki, nazarin hoto, da gwaje-gwajen dakin gwaje-gwaje. Tsarin bincike yawanci ya haɗa da:
Nazarin Hoto
Duban dan tayi na wuyansa yawanci shine mataki na farko, yana ba da damar hangen nesa na nodules na thyroid da lymphadenopathy. Ƙarin hoto, kamar CT or MRI, na iya zama dole don tantance girman cutar, musamman idan ana zargin metastasis.
Gwajin gwaje-gwaje
Serum calcitonin da matakan antigen carcinoembryonic (CEA) ana auna su azaman wani ɓangare na aikin bincike. Maɗaukakin matakan waɗannan alamomi suna nuni da MTC. Bugu da ƙari, ana ba da shawarar gwajin kwayoyin halitta don maye gurbin RET, musamman ga mutanen da ke da tarihin iyali da ke nuna MEN2.
Hanyoyin Biopsy
Burin allura mai kyau (FNA) biopsy na thyroid nodule yana ba da gwajin cytological, yana taimakawa tabbatar da ganewar ciwon daji na medullary thyroid. Binciken tarihi ya nuna halayen salon salula na MTC, yana bambanta shi da sauran cututtukan thyroid.
Medullary Thyroid Magani Zaɓuɓɓuka
Maganin ciwon daji na medullary thyroid da farko ya ƙunshi aikin tiyata, tare da jimlar thyroidectomy shine ginshiƙi. Anan ga ƙarin duban hanyoyin jiyya:
Hanyoyi na tiyata
- Jimlar Thyroidectomy: Cikakkiyar kawar da glandar thyroid yana da mahimmanci, sau da yawa tare da kawar da nodes na lymph da suka shafa (ragawar wuyansa na tsakiya) don gudanar da metastasis na yanki.
- Gyaran Rarraba wuyan Radical: A cikin lokuta inda shigar kumburin lymph ya yi yawa, mafi mahimmancin hanyar tiyata na iya zama dole don tabbatar da gamawar nama mai ciwon daji.
Magungunan marasa tiyata
Yayin da tiyata ya kasance jigon farko, ana iya la'akari da ƙarin hanyoyin kwantar da hankali:
- Radiation Far: Za a iya amfani da radiation bayan tiyata a lokuta inda ake zargin cututtuka na saura, kodayake rawar da ke cikin MTC ba shi da ma'ana fiye da sauran ciwon daji na thyroid.
- Manufa da hanyoyin kwantar da hankali: Ci gaba a cikin ilimin kwayoyin halitta ya haifar da haɓaka hanyoyin da aka yi niyya, irin su tyrosine kinase inhibitors (TKIs), waɗanda ke da fa'ida musamman a cikin ci gaba ko haɓakar MTC.
Kuna shirye don sarrafa tafiyar lafiyar ku? Yi lissafin alƙawarinku yanzu kuma fara hanyar ku zuwa lafiya a yau!
Littafin SanarwaHasashen Hasashen da Bibiya
Hasashen ciwon daji na medullary thyroid ya bambanta bisa ga dalilai da yawa, ciki har da mataki na cutar a ganewar asali, asalin kwayoyin halitta, da kuma mayar da martani ga magani. MTC na farko yana da ingantacciyar tsinkaya, tare da ƙimar rayuwa yana raguwa sosai tare da matakan ci gaba.
Gudanar da Dogon Lokaci
Bibiya na yau da kullun yana da mahimmanci ga mutanen da aka yi wa MTC magani, gami da:
- Kula da Alamar Serum: Tsayawa tsayin calcitonin da CEA bayan tiyata na iya nuna saura ko cuta mai maimaitawa, yana buƙatar ƙarin sa baki.
- Nazarin Hoto: Ana iya buƙatar hoto na lokaci-lokaci don saka idanu don sake dawowa ko metastasis.
Medullary Thyroid Ciwon daji da Shawarar Halitta
Ganin abubuwan da ke tattare da kwayoyin halittar MTC, musamman a cikin al'amuran iyali, shawarwarin kwayoyin halitta suna taka muhimmiyar rawa. Ya kamata a ba dangin mutanen da abin ya shafa a ba su gwajin kwayoyin halitta don gano masu ɗauke da maye gurbi na RET, da ba da damar sa baki da wuri da dabarun rigakafi.
Tambayoyin da
1. Menene Alamomin Medullary Thyroid Cancer?
Alamun na iya haɗawa da dunƙule a wuya, wahalar haɗiye, da kururuwa, wanda ke nuna ciwon daji na glandar thyroid.
2. Menene ke haifar da Ciwon daji na Thyroid?
Abubuwan da ke haifar da sau da yawa ana danganta su da maye gurbi, musamman a cikin iyalai masu ciwon neoplasia (MEN) da yawa.
3. Ta yaya Medullary Thyroid Cancer aka gano?
Ganowa yawanci ya ƙunshi gwajin jini don matakan calcitonin da nazarin hoto don tantance yaduwar ƙwayar cuta.
4. Menene zaɓuɓɓukan magani don Medullary Thyroid Cancer?
Jiyya yawanci ya haɗa da cire ƙwayar thyroid ta tiyata, tare da sa ido don sake dawowa da sarrafa alamun da ke hade.
5. Menene tsinkaya ga Medullary Thyroid Cancer?
Hasashen na iya bambanta ko'ina dangane da matakin ƙari da martani ga jiyya, yana buƙatar sa ido sosai.
